Evidence map›Paper›PMID 32377268›Full record

ArticleDisease markers2020

The Postoperative Lymphocyte to Monocyte Ratio Change Predicts Poor Clinical Outcome in Patients with Esophageal Squamous Cell Carcinoma Undergoing Curative Resection.

Qian Song, Jun-Zhou Wu, Hui-Fen Jiang, Sheng Wang, Shu-Nv Cai

Open access · hybridAbstract read
In one paragraph

Article in Disease markers, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.8field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 11 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Qian SongDepartment of Clinical Laboratory, Zhejiang Cancer Hospital, Institute of Cancer and Basic Medicine (ICBM), Chinese Academy of Sciences; Department of Clinical Laboratory, Cancer Hospital of the University of Chinese Academy of Sciences, Hangzhou, Zhejiang, China.ORCID https://orcid.org/0000-0003-4892-7537
Jun-Zhou WuZhejiang Cancer Hospital, Institute of Cancer and Basic Medicine (ICBM), Chinese Academy of Sciences; Cancer Research Institute, Cancer Hospital of the University of Chinese Academy of Sciences; Cancer Research Institute, Hangzhou, Zhejiang, China.ORCID https://orcid.org/0000-0001-6575-1743
Hui-Fen JiangDepartment of Clinical Laboratory, Zhejiang Cancer Hospital, Institute of Cancer and Basic Medicine (ICBM), Chinese Academy of Sciences; Department of Clinical Laboratory, Cancer Hospital of the University of Chinese Academy of Sciences, Hangzhou, Zhejiang, China.ORCID https://orcid.org/0000-0002-8115-3230
Sheng WangDepartment of Clinical Laboratory, Zhejiang Cancer Hospital, Institute of Cancer and Basic Medicine (ICBM), Chinese Academy of Sciences; Department of Clinical Laboratory, Cancer Hospital of the University of Chinese Academy of Sciences, Hangzhou, Zhejiang, China.ORCID https://orcid.org/0000-0002-3059-8897
Shu-Nv CaiDepartment of Anesthesiology, Zhejiang Cancer Hospital, Institute of Cancer and Basic Medicine (ICBM), Chinese Academy of Sciences; Department of Anesthesiology, Cancer Hospital of the University of Chinese Academy of Sciences, Hangzhou, Zhejiang, China.ORCID https://orcid.org/0000-0002-4684-6744
Zhejiang Cancer Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPostoperative lymphocyte to monocyte ratio (post-LMR) change (LMRc) reflects the dynamic change of balance between inflammatory reaction and immune reaction after curative operation. An elevated preoperative LMR (pre-LMR) has been shown to be a prognostic factor in patients with esophageal squamous cell carcinoma (ESCC), but the clinical value of the LMRc remains unknown.

methods674 patients in ESCC undergoing curative operation were enrolled in this study. LMRc (LMRc = pre-LMR-post-LMR) was counted on the basis of data within one week before and after operation. The median of LMRc was chosen to be the optimal cut-off value to evaluate the prognostic value of LMRc.

resultsKaplan-Meier curves revealed that LMRc ≤ 1.59 was significantly associated with worse overall survival (OS) (

conclusionsLMRc is a promising prognostic predictor for predicting the worse clinical outcome in patients with ESCC undergoing curative operation.

Indexed as

Biomarkers, TumorCarcinoma, Squamous CellEsophageal NeoplasmsFemaleHumansLeukocyte CountLymphocytesMaleMiddle AgedMonocytesTreatment OutcomeBiomarkers, Tumor

Identifiers

PMID32377268
PMCPMC7193282
OpenAlexW3017604014

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.