Evidence map›Paper›PMID 32377228›Full record

ArticleChinese medicine2020

Analysis of microRNA expression in peripheral blood monocytes of three Traditional Chinese Medicine (TCM) syndrome types in psoriasis patients.

Yue Lu, Yao Qi, Yuhong Yan, Danni Yao, Hao Deng, Jingwen Deng, Shuyan Ye, Haiming Chen, Qubo Chen, Hengjun Gao and 2 more

Open access · goldAbstract read
In one paragraph

Article in Chinese medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.3field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 9 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 1 country.

Yue Lu1Guangdong Provincial Hospital of Chinese Medicine, Guangzhou, 510006 Guangdong People's Republic of China.ORCID 0000-0002-5340-8398
Yao QiShanghai Molecular Medicine Engineering Technology Research Center, Shanghai, 201203 China.
Yuhong Yan1Guangdong Provincial Hospital of Chinese Medicine, Guangzhou, 510006 Guangdong People's Republic of China.
Danni Yao1Guangdong Provincial Hospital of Chinese Medicine, Guangzhou, 510006 Guangdong People's Republic of China.
Hao Deng1Guangdong Provincial Hospital of Chinese Medicine, Guangzhou, 510006 Guangdong People's Republic of China.
Jingwen Deng1Guangdong Provincial Hospital of Chinese Medicine, Guangzhou, 510006 Guangdong People's Republic of China.
Shuyan Ye1Guangdong Provincial Hospital of Chinese Medicine, Guangzhou, 510006 Guangdong People's Republic of China.
Haiming Chen1Guangdong Provincial Hospital of Chinese Medicine, Guangzhou, 510006 Guangdong People's Republic of China.
Qubo Chen1Guangdong Provincial Hospital of Chinese Medicine, Guangzhou, 510006 Guangdong People's Republic of China.
Hengjun GaoShanghai Molecular Medicine Engineering Technology Research Center, Shanghai, 201203 China.
Ling Han1Guangdong Provincial Hospital of Chinese Medicine, Guangzhou, 510006 Guangdong People's Republic of China.
Chuanjian Lu1Guangdong Provincial Hospital of Chinese Medicine, Guangzhou, 510006 Guangdong People's Republic of China.
Guangzhou University of Chinese Medicine · CNNational Engineering Research Center for Nanotechnology · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundTo analyze the expression of miRNA (microRNA) in peripheral blood mononuclear cells in patients with

methodsPeripheral blood monocytes were collected and prepared from 30 patients with

resultsCompared to the healthy control group, 156 upregulated and 242 downregulated miRNAs were detected in all psoriasis patients. Compared to the healthy control group, 40 miRNAs were upregulated and 44 were downregulated in the blood heat syndrome group. Furthermore, there were 49 upregulated miRNAs and 44 downregulated miRNAs in the dry syndrome group as compared to the healthy control group. Also, 67 miRNAs were upregulated and 154 miRNAs were downregulated in the blood stasis syndrome group as compared to the healthy control group.

conclusionsThere are common different miRNAs and pathways, as well as specific miRNAs between the psoriasis and the healthy control groups.

Indexed as

miRNA chipmiRNA expressionPsoriasisTCM syndrome type

Identifiers

PMID32377228
PMCPMC7193417
OpenAlexW3020938552

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.