Evidence map›Paper›PMID 32377223›Full record

ArticleComputational and mathematical methods in medicine2020

In Silico Analysis Identifies Differently Expressed lncRNAs as Novel Biomarkers for the Prognosis of Thyroid Cancer.

Yuansheng Rao, Haiying Liu, Xiaojuan Yan, Jianhong Wang

Open access · hybridAbstract read
In one paragraph

Article in Computational and mathematical methods in medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
2.2field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 34 citations in OpenAlex.

  1. Oncogenic role of LncRNA DLEU2 in thyroid cancer through a NAT10/USP39 regulatory axis.Mammalian genome : official journal of the International Mammalian Genome Society · 2026
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  11. Personalized 3-Gene Panel for Prostate Cancer Target Therapy.Current issues in molecular biology · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Yuansheng RaoDepartment of Otorhinolaryngology, Beijing Anzhen Hospital, No. 2 Anzhen Road, Chaoyang District, Beijing 100029, China.
Haiying LiuDepartment of Otorhinolaryngology, Beijing Anzhen Hospital, No. 2 Anzhen Road, Chaoyang District, Beijing 100029, China.
Xiaojuan YanDepartment of Otorhinolaryngology, Beijing Anzhen Hospital, No. 2 Anzhen Road, Chaoyang District, Beijing 100029, China.
Jianhong WangDepartment of Otorhinolaryngology, Beijing Anzhen Hospital, No. 2 Anzhen Road, Chaoyang District, Beijing 100029, China.ORCID https://orcid.org/0000-0001-9695-6215
Beijing Anzhen Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThyroid cancer (TC) is one of the most common type of endocrine tumors. Long noncoding RNAs had been demonstrated to play key roles in TC.

resultsIn the present study, we identified 6 upregulated and 85 downregulated lncRNAs in TC samples. Moreover, we for the first time identified 16 downregulated lncRNAs was correlated to longer disease-free survival time in patients with TC, including ATP1A1-AS1, CATIP-AS1, FAM13A-AS1, LINC00641, LINC00924, MIR22HG, NDUFA6-AS1, RP11-175K6.1, RP11-727A23.5, RP11-774O3.3, RP13-895J2.2, SDCBP2-AS1, SLC26A4-AS1, SNHG15, SRP14-AS1, and ZNF674-AS1.

conclusionsBioinformatics analysis revealed these lncRNAs were involved in regulating the RNA metabolic process, cell migration, organelle assembly, tRNA modification, and hormone levels. This study will provide useful information to explore the potential candidate biomarkers for diagnosis, prognosis, and drug targets for TC.

Indexed as

Biomarkers, TumorComputational BiologyComputer SimulationDatabases, Nucleic AcidDisease-Free SurvivalGene Expression ProfilingGene Expression Regulation, NeoplasticGene OntologyGene Regulatory NetworksHumansKaplan-Meier EstimatePrognosisRNA, Long NoncodingRNA, MessengerThyroid NeoplasmsBiomarkers, TumorRNA, Long NoncodingRNA, Messenger

Identifiers

PMID32377223
PMCPMC7195652
OpenAlexW3018778542

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.