ArticleInternational journal of dentistry2020
Morphology, Volume, and Density Characteristics of the Parotid Glands before and after Chemoradiation Therapy in Patients with Head and Neck Tumors.
Article in International journal of dentistry, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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Who cites it
7 citing papers in PubMed, 9 citations in OpenAlex.
- Machine learning-based radiomics for histological classification of parotid tumors using morphological MRI: a comparative study.European radiology · 2022Trial
- Examination of parotid gland in diabetics with ultrasound elastography and microvascular imaging.Medicina oral, patologia oral y cirugia bucal · 2025Article
- Article
- Three-Dimensional Volumetric Analysis of Frontal Ethmoidal Cells and Evaluation of Influential Factors: A Helical Computed Tomography Study.Tomography (Ann Arbor, Mich.) · 2022Article
- Population Based Average Parotid Gland Volume and Prevalence of Incidental Tumors in T1-MRI.Healthcare (Basel, Switzerland) · 2022Article
- Influence of post-label delay time on the performance of 3D pseudo-continuous arterial spin labeling magnetic resonance imaging in the characterization of parotid gland tumors.European radiology · 2022Article
- The Diagnostic Value of Ultrasound-Based Deep Learning in Differentiating Parotid Gland Tumors.Journal of oncology · 2022Article
Corrections and comments
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Authors and funding
9 authors at 4 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The multimodal approach for patients with head and neck cancer (HNC) includes treatment with chemoradiation therapy (CRT). A common concern regarding CRT side effects is the occurrence of structural and physiological alterations of the salivary glands due to exposure to ionizing radiation. The aim of this study is to examine the morphology, volume, and density of the parotid glands before and after CRT in HNC patients. A total of 49 HNC patients treated exclusively with CRT were included in the study. Ninety-eight parotid glands were evaluated before and after treatment by using contrast-enhanced computed tomography (CECT). Shapiro-Wilk test was performed, and the variables (pre-CRT and post-CRT) presented normal distribution. Pearson's coefficient was used to assess the correlation between volume and density. CRT resulted in a significant decrease in the mean volume of the parotid glands (i.e., original volume reduced by 20.5%;
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Registered trials
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