Evidence map›Paper›PMID 32377166›Full record

ArticleMediators of inflammation2020

Diallyl Disulfide Suppresses Inflammatory and Oxidative Machineries following Carrageenan Injection-Induced Paw Edema in Mice.

Hongxing Zhang, Chi Shang, Zhao Tian, Hatem K Amin, Rami B Kassab, Ahmed E Abdel Moneim, Yingang Zhang

Open access · goldAbstract read
In one paragraph

Article in Mediators of inflammation, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed
9.0field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 62 citations in OpenAlex.

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  12. Metabolic Composition of Methanolic Extract of the Balkan Endemic SpeciesInternational journal of molecular sciences · 2024
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  14. Fucoidan fromBiomedicines · 2023
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  17. Metabolite Profiling ofMolecules (Basel, Switzerland) · 2022
    Article
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  20. Elucidation of the Metabolite Profile ofMolecules (Basel, Switzerland) · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 3 countries.

Hongxing ZhangDepartment of Orthopaedic Surgery, The First Affiliated Hospital of Xi'an Jiaotong University, No. 277 West Yanta Road, Yanta District, Xi'an, Shaanxi 710061, China.
Chi ShangDepartment of Hand Surgery, Xi'an Honghui Hospital, No. 555 Youyi East Road, Beilin District, Xi'an, Shaanxi 710054, China.
Zhao TianDepartment of Hand Surgery, Xi'an Honghui Hospital, No. 555 Youyi East Road, Beilin District, Xi'an, Shaanxi 710054, China.
Hatem K AminDepartment of Biochemistry and Molecular Biology, Faculty of Pharmacy, Helwan University, Cairo 11795, Egypt.
Rami B KassabZoology and Entomology Department, Faculty of Science, Helwan University, Cairo 11795, Egypt.ORCID https://orcid.org/0000-0002-1520-1601
Ahmed E Abdel MoneimZoology and Entomology Department, Faculty of Science, Helwan University, Cairo 11795, Egypt.ORCID https://orcid.org/0000-0002-2654-2591
Yingang ZhangDepartment of Orthopaedic Surgery, The First Affiliated Hospital of Xi'an Jiaotong University, No. 277 West Yanta Road, Yanta District, Xi'an, Shaanxi 710061, China.ORCID https://orcid.org/0000-0002-4484-3742
First Affiliated Hospital of Xi'an Jiaotong University · CNHelwan University · EGXi'an Honghui Hospital · CNAl Baha University · SA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Diallyl disulfide (DADS) is the major organosulfur constituent in garlic, with a variety of pharmacological activities including antioxidant and anti-inflammatory. Here, we examined the potential antiedematous impact of DADS- versus carrageenan-mediated paw edema in mice. Carrageenan injection potentiated an inflammatory reaction as presented by the elevated serological C-reactive protein (CRP) levels and transcription of tumor necrosis factor-alpha (TNF-

Indexed as

Allyl CompoundsAnimalsAnti-Inflammatory AgentsCarrageenanC-Reactive ProteinCyclooxygenase 2CytokinesDisulfidesEdemaMaleMiceNF-kappa BNitric Oxide Synthase Type IIOxidative StressPeroxidaseAllyl CompoundsAnti-Inflammatory AgentsCarrageenanC-Reactive ProteinCyclooxygenase 2Cytokinesdiallyl disulfideDisulfidesNF-kappa BNitric Oxide Synthase Type IINos2 protein, mousePeroxidasePtgs2 protein, mouse

Identifiers

PMID32377166
PMCPMC7180418
OpenAlexW3016455563

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.