Evidence map›Paper›PMID 32377160›Full record

ArticleMediators of inflammation2020

Decreased Plasma Maresin 1 Concentration Is Associated with Diabetic Foot Ulcer.

Tian Miao, Bangliang Huang, Niexia He, Lihua Sun, Guangsheng Du, Xiaoli Gong, Yong Xu, Yi Zheng, Hongting Zheng, Hua Qu

Open access · goldAbstract read
In one paragraph

Article in Mediators of inflammation, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed, 2 pooled it
2.6field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 2 syntheses or guidelines pooled it, 24 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Article
  5. Defective efferocytosis in diabetes: molecular mechanisms and emerging therapeutic strategies.Inflammation research : official journal of the European Histamine Research Society ... [et al.] · 2026
    Review
  6. Article
  7. Maresins.Biomolecules · 2026
    Review
  8. Review
  9. Review
  10. Review
  11. Article
  12. Plasma Asprosin Concentrations are Associated with Progression of Diabetic Kidney Disease.Diabetes, metabolic syndrome and obesity : targets and therapy · 2024
    Article
  13. Review
  14. Review
  15. Article
  16. Protective Potential of Maresins in Cardiovascular Diseases.Frontiers in cardiovascular medicine · 2022
    Review
  17. Article
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Tian MiaoDepartment of Endocrinology, Translational Research of Diabetes Key Laboratory of Chongqing Education Commission of China, The Second Affiliated Hospital of Army Medical University, Chongqing, China.
Bangliang HuangDepartment of Endocrinology, Translational Research of Diabetes Key Laboratory of Chongqing Education Commission of China, The Second Affiliated Hospital of Army Medical University, Chongqing, China.
Niexia HeDepartment of Ultrasound, The Second Affiliated Hospital of Army Medical University, Chongqing, China.
Lihua SunDepartment of General Surgery, The Second Affiliated Hospital of Army Medical University, Chongqing, China.
Guangsheng DuDepartment of General Surgery, The Second Affiliated Hospital of Army Medical University, Chongqing, China.
Xiaoli GongDepartment of Endocrinology, Translational Research of Diabetes Key Laboratory of Chongqing Education Commission of China, The Second Affiliated Hospital of Army Medical University, Chongqing, China.
Yong XuDepartment of Diabetes and Endocrinology, Affiliated Hospital of Southwest Medical University, Luzhou, Sichuan, China.ORCID https://orcid.org/0000-0002-9534-6252
Yi ZhengDepartment of Endocrinology, Translational Research of Diabetes Key Laboratory of Chongqing Education Commission of China, The Second Affiliated Hospital of Army Medical University, Chongqing, China.ORCID https://orcid.org/0000-0002-5945-4432
Hongting ZhengDepartment of Endocrinology, Translational Research of Diabetes Key Laboratory of Chongqing Education Commission of China, The Second Affiliated Hospital of Army Medical University, Chongqing, China.ORCID https://orcid.org/0000-0002-6930-0103
Hua QuDepartment of Endocrinology, Translational Research of Diabetes Key Laboratory of Chongqing Education Commission of China, The Second Affiliated Hospital of Army Medical University, Chongqing, China.ORCID https://orcid.org/0000-0002-4895-5979
Army Medical University · CNAffiliated Hospital of Southwest Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimsTo assess the maresin 1 (MaR1) contents in type 2 diabetic patients with or without diabetic foot ulcer and to analyze the association of MaR1 concentrations with several metabolism-related parameters.

methodsPlasma MaR1 concentrations were analyzed in 96 subjects with normal glucose tolerant (NC,

resultsPlasma MaR1 concentrations were significant decreased in type 2 diabetes patient with or without DFU compared with NC (both

conclusionsPlasma MaR1 concentration were decreased in T2DM with or without DFUs and were the lowest in DFU patients. The decreased plasma MaR1 strongly associated with obesity, impaired glucose and lipid metabolism, reduced first-phase of glucose-stimulated insulin secretion, and enhanced insulin resistance.

Indexed as

AdultAgedDiabetic FootDocosahexaenoic AcidsFemaleGlucoseHumansInsulin ResistanceLipid MetabolismMaleMiddle Aged7,14-dihydroxydocosa-4,8,10,12,16,19-hexaenoic acidDocosahexaenoic AcidsGlucose

Identifiers

PMID32377160
PMCPMC7182968
OpenAlexW3017141320

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.