ReviewPhysiology and molecular biology of plants : an international journal of functional plant biology2020
Multigene CRISPR/Cas9 genome editing of hybrid proline rich proteins (HyPRPs) for sustainable multi-stress tolerance in crops: the review of a promising approach.
Review in Physiology and molecular biology of plants : an international journal of functional plant biology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed, 27 citations in OpenAlex.
- Chloroplast Functionality at the Interface of Growth, Defense, and Genetic Innovation: A Multi-Omics and Technological Perspective.Plants (Basel, Switzerland) · 2025Review
- Multi-Omics Approaches Against Abiotic and Biotic Stress-A Review.Plants (Basel, Switzerland) · 2025Review
- Proline Tagging for Stress Tolerance in Plants.International journal of genomics · 2025Review
- Lipid peroxidation and stress-induced signalling molecules in systemic resistance mediated by azelaic acid/AZELAIC ACID INDUCED1: signal initiation and propagation.Physiology and molecular biology of plants : an international journal of functional plant biology · 2024Review
- CRISPR/Cas9-based genome editing and functional analysis ofFrontiers in plant science · 2024Article
- A breeding strategy for improving drought and salt tolerance of poplar based on CRISPR/Cas9.Plant biotechnology journal · 2023Article
- The ubiquitin-binding protein MdRAD23D1 mediates drought response by regulating degradation of the proline-rich protein MdPRP6 in apple (Malus domestica).Plant biotechnology journal · 2023Article
- Gene Editing for Plant Resistance to Abiotic Factors: A Systematic Review.Plants (Basel, Switzerland) · 2023Review
- Intriguing Role of Proline in Redox Potential Conferring High Temperature Stress Tolerance.Frontiers in plant science · 2022Review
- BSR-Seq analysis provides insights into the cold stress response of Actinidia arguta F1 populations.BMC genomics · 2021Article
- Physiology and molecular biology of plants : an international journal of functional plant biology · 2020Article
Corrections and comments
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Authors and funding
7 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The recent global climate change has directly impacted major biotic and abiotic stress factors affecting crop productivity worldwide. Therefore, the need of the hour is to develop sustainable multiple stress tolerant crops through modern biotechnological approaches to cope with climate change. Hybrid proline rich proteins (HyPRPs) are the cell-wall structural proteins, which contain an N-terminal repetitive proline-rich domain and a C-terminal conserved eight-cysteine motif domain. HyPRPs are known to regulate multiple abiotic and biotic stress responses in plants. Recently, a few HyPRPs have been characterized as negative regulators of abiotic and biotic stress responses in different plants. Disruption of such negative regulators for desirable positive phenotypic traits has been made possible through the advent of advanced genome engineering tools. In the past few years, CRISPR/Cas9 has emerged as a novel breakthrough technology for crop improvement by target specific editing of known negative regulatory host genes. Here, we have described the mechanism of action and the role of known HyPRPs in regulating different biotic and abiotic stress responses in major crop plants. We have also discussed the importance of the CRISPR/Cas9 based genome editing system in targeting known negative regulatory HyPRPs for multi-stress crop tolerance using the tomato crop model. Application of genome editing to manipulate the HyPRPs of major crop plants holds promise in developing newer stress management methods in this rapidly changing climate and would lead in the future to sustain crop productivity.
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