Evidence map›Paper›PMID 32376865›Full record

ArticleScientific reports2020

Dopaminergic Plasticity in the Bilateral Hippocampus Following Threat Reversal in Humans.

Jennifer I Lissemore, Atsuko Nagano-Saito, Kelly Smart, Paul Gravel, Marco Leyton, Chawki Benkelfat

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.4field-weighted citation impact, top 47% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 4 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Jennifer I LissemoreDepartment of Psychiatry, McGill University, 1033 Pine Avenue West, Montreal, H3A 1A1, Quebec, Canada. jennifer.lissemore@mail.mcgill.ca.
Atsuko Nagano-SaitoDepartment of Psychiatry, McGill University, 1033 Pine Avenue West, Montreal, H3A 1A1, Quebec, Canada.
Kelly SmartDepartment of Psychiatry, McGill University, 1033 Pine Avenue West, Montreal, H3A 1A1, Quebec, Canada.ORCID http://orcid.org/0000-0002-4775-6943
Paul GravelDepartment of Psychiatry, McGill University, 1033 Pine Avenue West, Montreal, H3A 1A1, Quebec, Canada.
Marco LeytonDepartment of Psychiatry, McGill University, 1033 Pine Avenue West, Montreal, H3A 1A1, Quebec, Canada.ORCID http://orcid.org/0000-0002-1243-2252
Chawki BenkelfatDepartment of Psychiatry, McGill University, 1033 Pine Avenue West, Montreal, H3A 1A1, Quebec, Canada.
McGill University · CAMontreal Neurological Institute and Hospital · CA

Funding

Gouvernement du Canada | Canadian Institutes of Health Research (Instituts de Recherche en Santé du Canada) MOP-119509
6 · The paper itself

Abstract

When a cue no longer predicts a threat, a diminished ability to extinguish or reverse this association is thought to increase risk for stress-related disorders. Despite the clear clinical relevance, the mediating neurochemical mechanisms of threat reversal have received relatively little study. One neurotransmitter implicated in rodent research of changing associations with threat is dopamine. To study whether dopamine is involved in threat reversal in humans, we used high-resolution positron emission tomography (PET) coupled with

Indexed as

Neuronal PlasticityAdultConditioning, PsychologicalCuesDopamineFemaleHealthy VolunteersHippocampusHumansMalePositron-Emission TomographyDopamine

Identifiers

PMID32376865
PMCPMC7203150
OpenAlexW3021088123

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.