Evidence map›Paper›PMID 32376752›Full record

ArticleBMJ open2020

Women's self-reported experiences using misoprostol obtained from drug sellers: a prospective cohort study in Lagos State, Nigeria.

Melissa Stillman, Onikepe Owolabi, Adesegun O Fatusi, Akanni I Akinyemi, Amanda L Berry, Temitope P Erinfolami, Olalekan S Olagunju, Heini Väisänen, Akinrinola Bankole

Abstract read
In one paragraph

Article in BMJ open, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 45 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
45citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

45 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Medical abortion offered in pharmacy versus clinic-based settings.The Cochrane database of systematic reviews · 2021
    Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Melissa StillmanDepartment of Research, Guttmacher Institute, New York, New York, USA mstillman@guttmacher.org.ORCID 0000-0002-1318-2419
Onikepe OwolabiDepartment of Research, Guttmacher Institute, New York, New York, USA.ORCID 0000-0002-4150-9976
Adesegun O FatusiDepartment of Research, Guttmacher Institute, New York, New York, USA.ORCID 0000-0002-3893-8024
Akanni I AkinyemiDepartment of Global Health and Population, Harvard T H Chan School of Public Health, Boston, Massachusetts, United States.ORCID 0000-0001-8652-9359
Amanda L BerryDepartment of Research, Guttmacher Institute, New York, New York, USA.ORCID 0000-0001-9084-7771
Temitope P ErinfolamiDepartment of Demography and Social Statistics, Obafemi Awolowo University, Ile-Ife, Nigeria.ORCID 0000-0001-6576-398X
Olalekan S OlagunjuDepartment of Demography and Social Statistics, Obafemi Awolowo University, Ile-Ife, Nigeria.ORCID 0000-0001-8394-133X
Heini VäisänenDepartment of Social Statistics and Demography, University of Southampton, Southampton, Hampshire, UK.ORCID 0000-0002-5494-0415
Akinrinola BankoleDepartment of Research, Guttmacher Institute, New York, New York, USA.ORCID 0000-0003-3220-9477

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesThis study aimed to assess the safety and effectiveness of self-managed misoprostol abortions obtained outside of the formal health system in Lagos State, Nigeria.

designThis was a prospective cohort study among women using misoprostol-containing medications purchased from drug sellers. Three telephone-administered surveys were conducted over 1 month.

settingData were collected in 2018 in six local government areas in Lagos State.

participantsDrug sellers attempted to recruit all women who purchased misoprostol-containing medication. To remain in the study, participants had to be female and aged 18-49, and had to have purchased the medication for the purpose of abortion. Of 501 women initially recruited, 446 were eligible for the full study, and 394 completed all three surveys. PRIMARY AND SECONDARY OUTCOME MEASURES: Using self-reported measures, we assessed the quality of information provided by drug sellers; the prevalence of potential complications; and the proportion with completed abortions.

resultsAlthough drug sellers provided inadequate information about the pills, 94% of the sample reported a complete abortion without surgical intervention about 1 month after taking the medication. Assuming a conservative scenario where all individuals lost to follow-up had failed terminations, the completion rate dropped to 87%. While 86 women reported physical symptoms suggestive of complications, only six of them reported wanting or needing health facility care and four subsequently obtained care.

conclusionsDrug sellers are an important source of medical abortion in this setting. Despite the limitations of self-report, many women appear to have effectively self-administered misoprostol. Additional research is needed to expand the evidence on the safety and effectiveness of self-use of misoprostol for abortion in restrictive settings, and to inform approaches that support the health and well-being of people who use this method of abortion.

Indexed as

Self ReportAbortifacient Agents, NonsteroidalAdolescentAdultAllied Health PersonnelFemaleHumansMiddle AgedMisoprostolNigeriaPrivate SectorProspective StudiesSurveys and QuestionnairesAbortifacient Agents, NonsteroidalMisoprostolgynaecologyinternational health servicespublic healthquality in health carereproductive medicine

Identifiers

PMID32376752
PMCPMC7223139

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.