Evidence map›Paper›PMID 32376702›Full record

Trial reportmSphere2020

Genetic Association Reveals Protection against Recurrence of

Judong Shen, Devan V Mehrotra, Mary Beth Dorr, Zhen Zeng, Junhua Li, Xun Xu, David Nickle, Emily R Holzinger, Aparna Chhibber, Mark H Wilcox and 2 more

Open access · goldAbstract readClinical Trial, Phase IIIRandomized Controlled Trial
In one paragraph

Trial report in mSphere, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
0.3field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it, 18 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. Article
  5. Review
  6. Article
  7. Review
  8. Host Immune Responses toFrontiers in microbiology · 2021
    Review
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 3 countries.

Judong ShenMerck & Co., Inc., Kenilworth, New Jersey, USA.
Devan V MehrotraMerck & Co., Inc., Kenilworth, New Jersey, USA.
Mary Beth DorrMerck & Co., Inc., Kenilworth, New Jersey, USA.
Zhen ZengMerck & Co., Inc., Kenilworth, New Jersey, USA.
Junhua LiBGI-Shenzhen, Shenzhen, China.
Xun XuBGI-Shenzhen, Shenzhen, China.
David NickleMerck & Co., Inc., Kenilworth, New Jersey, USA.
Emily R HolzingerMerck & Co., Inc., Kenilworth, New Jersey, USA.
Aparna ChhibberMerck & Co., Inc., Kenilworth, New Jersey, USA.
Mark H WilcoxLeeds Teaching Hospital and University of Leeds, Leeds, United Kingdom.
Rebecca L BlanchardMerck & Co., Inc., Kenilworth, New Jersey, USA.
Peter M ShawMerck & Co., Inc., Kenilworth, New Jersey, USA peter_shaw3@merck.com.
Merck & Co., Inc., Rahway, NJ, USA (United States) · USBGI Group (China) · CNLeeds Teaching Hospitals NHS Trust · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Bezlotoxumab is a human monoclonal antibody against

Indexed as

AdolescentAdultAgedAged, 80 and overAllelesAntibodies, MonoclonalAntibodies, NeutralizingBroadly Neutralizing AntibodiesClostridioides difficileClostridium InfectionsFemaleGenome-Wide Association StudyGenotypeHLA-D AntigensHumansMaleAntibodies, MonoclonalAntibodies, NeutralizingbezlotoxumabBroadly Neutralizing AntibodiesHLA-D AntigensantibacterialsbezlotoxumabClostridium difficilegenomics

Identifiers

PMID32376702
PMCPMC7203456
OpenAlexW3022241272

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.