Evidence map›Paper›PMID 32376617›Full record

ArticleDevelopment (Cambridge, England)2020

Sonic hedgehog specifies flight feather positional information in avian wings.

Lara Busby, Cristina Aceituno, Caitlin McQueen, Constance A Rich, Maria A Ros, Matthew Towers

Open access · hybridAbstract read
In one paragraph

Article in Development (Cambridge, England), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
0.9field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 18 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Review
  8. Article
  9. Article
  10. Patterning of theFrontiers in cell and developmental biology · 2023
    Review
  11. Regional specific differentiation of integumentary organs: SATB2 is involved in α- and β-keratin gene cluster switching in the chicken.Developmental dynamics : an official publication of the American Association of Anatomists · 2022
    Article
  12. Assessing evolutionary and developmental transcriptome dynamics in homologous cell types.Developmental dynamics : an official publication of the American Association of Anatomists · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Lara BusbyDepartment of Biomedical Science, University of Sheffield, Western Bank, Sheffield S10 2TN, UK.
Cristina AceitunoInstituto de Biomedicina y Biotecnología de Cantabria, IBBTEC (CSIC-Universidad de Cantabria - SODERCAN), 39011 Santander, Spain.
Caitlin McQueenDepartment of Biomedical Science, University of Sheffield, Western Bank, Sheffield S10 2TN, UK.
Constance A RichDepartment of Biomedical Science, University of Sheffield, Western Bank, Sheffield S10 2TN, UK.
Maria A RosInstituto de Biomedicina y Biotecnología de Cantabria, IBBTEC (CSIC-Universidad de Cantabria - SODERCAN), 39011 Santander, Spain m.towers@sheffield.ac.uk marian.ros@unican.es.ORCID 0000-0002-1224-7671
Matthew TowersDepartment of Biomedical Science, University of Sheffield, Western Bank, Sheffield S10 2TN, UK m.towers@sheffield.ac.uk marian.ros@unican.es.ORCID 0000-0003-2189-4536
University of Sheffield · GBUniversidad de Cantabria · ES

Funding

Wellcome Trust 202756/Z/16/Z
6 · The paper itself

Abstract

Classical tissue recombination experiments performed in the chick embryo provide evidence that signals operating during early limb development specify the position and identity of feathers. Here, we show that Sonic hedgehog (Shh) signalling in the embryonic chick wing bud specifies positional information required for the formation of adult flight feathers in a defined spatial and temporal sequence that reflects their different identities. We also reveal that Shh signalling is interpreted into specific patterns of

Indexed as

AnimalsBasic Helix-Loop-Helix ProteinsBirdsEmbryonic DevelopmentFeathersGene Expression Regulation, DevelopmentalHedgehog ProteinsSequence Analysis, RNASignal TransductionWings, AnimalBasic Helix-Loop-Helix ProteinsHedgehog ProteinsAvianChickEmbryoFlight featherPositional informationShh

Identifiers

PMID32376617
PMCPMC7225127
OpenAlexW3023681654

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.