Evidence map›Paper›PMID 32376586›Full record

ReviewNan fang yi ke da xue xue bao = Journal of Southern Medical University2020

[Application of self-propelled micro-/nanomotors in active targeted drug delivery].

Meihuan Liu, Binbin Tu, Lu Liu, Bin Chen, Yingfeng Tu

Open access · greenAbstract readReview
In one paragraph

Review in Nan fang yi ke da xue xue bao = Journal of Southern Medical University, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.2field-weighted citation impact, top 50% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Meihuan LiuSchool of Pharmaceutical Science, Guangdong Provincial Key Laboratory of New Drug Screening, Southern Medical University, Guangzhou 510515, China.
Binbin TuDepartment of Obstetrics and Gynecology, Peking University Third Hospital, Beijing 100191, Chin.
Lu LiuSchool of Pharmaceutical Science, Guangdong Provincial Key Laboratory of New Drug Screening, Southern Medical University, Guangzhou 510515, China.
Bin ChenSchool of Pharmaceutical Science, Guangdong Provincial Key Laboratory of New Drug Screening, Southern Medical University, Guangzhou 510515, China.
Yingfeng TuSchool of Pharmaceutical Science, Guangdong Provincial Key Laboratory of New Drug Screening, Southern Medical University, Guangzhou 510515, China.
Southern Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

As a new type of micro-/nanomachines, self-propelled micro-/nanomotors (MNMs) can convert chemical or external energies from the surrounding environment into mechanical forces to produce autonomous motion. The ability of autonomous movement allows these MNMs to move actively to the targeted locations, and thus confers great potentials on the MNMs for applications in biomedicine, especially in drug delivery. MNMs have been shown to effectively load therapeutic payloads for active delivery to the disease site, which greatly improves the therapeutic efficacy and reduces side effects compared with the traditional nanodrugs. In this review, we provide an overview of different propulsion mechanisms of MNMs, including chemical propulsion based on redox reaction and external field propulsion driven by external energy such as light, magnetic field, electric field and ultrasound, followed by a review of the recent progress in active drug delivery based on MNMs in the past decade. We also discuss the current challenges and future perspectives of the application of the MNMs.

Indexed as

NanostructuresNanotechnologyDrug Delivery SystemsMotionOxidation-Reductionchemically propulsiondrug deliveryexternal field propulsionmicro-/nanomotors

Identifiers

PMID32376586
PMCPMC7167322
OpenAlexW3028177759

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.