Evidence map›Paper›PMID 32376485›Full record

ArticleThe journal of allergy and clinical immunology. In practice2020

Egg Allergy in US Children.

Waheeda Samady, Christopher Warren, Julie Wang, Rajeshree Das, Ruchi S Gupta

Open access · greenAbstract read
In one paragraph

Article in The journal of allergy and clinical immunology. In practice, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed
5.6field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 70 citations in OpenAlex.

  1. Trial
  2. Recent Advances in Food Allergens and Emerging Biosensing Technologies.Comprehensive reviews in food science and food safety · 2026
    Review
  3. Article
  4. Review
  5. Article
  6. Review
  7. Review
  8. Article
  9. Article
  10. Review
  11. Effects of Food Processing on Allergenicity.Current allergy and asthma reports · 2025
    Review
  12. Review
  13. Food Matrix Composition Affects the Allergenicity of Baked Egg Products.The journal of allergy and clinical immunology. In practice · 2024
    Article
  14. Review
  15. Review
  16. Article
  17. Article
  18. Article
  19. The epidemiology of multifood allergy in the United States: A population-based study.Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology · 2023
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Waheeda SamadyCenter for Food Allergy and Asthma Research, Northwestern University Feinberg School of Medicine, Chicago, Ill; Division of Hospital Based Medicine, Ann & Robert H. Lurie Children's Hospital of Chicago, Chicago, Ill.
Christopher WarrenCenter for Food Allergy and Asthma Research, Northwestern University Feinberg School of Medicine, Chicago, Ill; Sean N. Parker Center for Allergy and Asthma Research, Stanford University School of Medicine, Stanford, Calif.
Julie WangDivision of Allergy and Immunology, Department of Pediatrics, The Elliot and Roslyn Jaffe Food Allergy Institute, Icahn School of Medicine at Mount Sinai, New York, NY.
Rajeshree DasCenter for Food Allergy and Asthma Research, Northwestern University Feinberg School of Medicine, Chicago, Ill.
Ruchi S GuptaCenter for Food Allergy and Asthma Research, Northwestern University Feinberg School of Medicine, Chicago, Ill; Division of Academic General Pediatrics, Ann & Robert H. Lurie Children's Hospital of Chicago, Chicago, IL. Electronic address: r-gupta@northwestern.edu.
Northwestern University · USIcahn School of Medicine at Mount Sinai · USStanford University · US

Funding

FORWARD Supplement Standardizing EHR Data CollectionR01AI130348 · NIAID · NORTHWESTERN UNIVERSITY AT CHICAGO · PI Ruchi S Gupta · 2017 to 2026
$10.9M
Intervention to Reduce Early (Peanut) Allergy in Children (iREACH)U01AI138907 · NIAID · LURIE CHILDREN'S HOSPITAL OF CHICAGO · PI GUPTA, RUCHI S · 2019 to 2023
$8.0M
US Prevalence, Distribution and Determinants of Adult and Childhood Food AllergyR21AI135702 · NIAID · LURIE CHILDREN'S HOSPITAL OF CHICAGO · PI GUPTA, RUCHI S · 2018 to 2019
$433k
NIAID NIH HHS R01 AI130348NIAID NIH HHS R21 AI135702NIAID NIH HHS U01 AI138907
6 · The paper itself

Abstract

backgroundEgg allergy is common in young children (<5 years) and has significant negative impacts on quality of life.

objectiveThe objective of this study was to characterize egg allergy prevalence, severity, baked egg tolerance, and other associated factors in a large US cohort.

methodsA national cross-sectional survey was administered from October 2015 to September 2016, resulting in complete parent-proxy responses for 38,408 children. Weighted proportions were estimated to compare egg allergy prevalence and characteristics between key subpopulations.

resultsThe overall prevalence of current, convincingly egg allergy was 0.9% among all children and 1.3% among children <5 years. Black children were over-represented among children with egg allergy, accounting for 23.4% (95% confidence interval: 13.1-38.4) of egg-allergic children despite comprising 13.2% (12.3-14.2) of the US pediatric population. Among children with egg allergy, 64.2% reported baked egg tolerance and 60.2% had allergy to other foods, with 29.3% having peanut allergy. Asthma was more prevalent in children with an egg allergy than children with other top 8 food allergies (46.5% [35.8-57.4] vs 33.2% [29.6-37.0], P < .05). Among children with current egg allergy, those with baked egg tolerance reported that their food allergy resulted in significantly reduced psychosocial burden, relative to their baked egg-allergic counterparts (M = 3.1 [2.9-3.3] vs M = 3.7 [3.5-3.9]).

conclusionsEgg allergy is common amongst young children. Nearly two-thirds of children with egg allergy reported baked egg tolerance. Increased efforts are needed to ensure that children with egg allergy are appropriately evaluated as many have comorbid allergic disease and determination of baked egg tolerance may improve quality of life.

Indexed as

Egg HypersensitivityFood HypersensitivityPeanut HypersensitivityChildChild, PreschoolCross-Sectional StudiesHumansQuality of LifeAtopyEgg allergyFood allergyPediatricsPrevalence

Identifiers

PMID32376485
PMCPMC7895443
OpenAlexW3021973418

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.