Evidence map›Paper›PMID 32376035›Full record

ArticleTrends in neurosciences2020

Connecting Pathological Cellular Mechanisms to Large-Scale Seizure Structures.

Quynh-Anh Nguyen, Prannath Moolchand, Ivan Soltesz

Open access · greenAbstract readComment
PubMed Full text at PMC Publisher
In one paragraph

Article in Trends in neurosciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.5field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Quynh-Anh NguyenDepartment of Neurosurgery, Stanford University, Stanford, CA 94305, USA.
Prannath MoolchandDepartment of Neurosurgery, Stanford University, Stanford, CA 94305, USA.
Ivan SolteszDepartment of Neurosurgery, Stanford University, Stanford, CA 94305, USA. Electronic address: isoltesz@stanford.edu.
Stanford University · US

Funding

Closed-loop intervention in epilepsy.R01NS094668 · NINDS · STANFORD UNIVERSITY · PI LOSONCZY, ATTILA, SOLTESZ, IVAN · 2015 to 2019
$2.3M
Dissecting the function of the B3 subunit of the GABAA receptor ex vivo and in vivoF32NS106764 · NINDS · STANFORD UNIVERSITY · PI NGUYEN, QUYNH ANH · 2018 to 2020
$153k
NINDS NIH HHS F32 NS106764NINDS NIH HHS R01 NS094668
6 · The paper itself

Abstract

Epilepsy is a neurological disorder characterized by recurrent seizures, where abnormal electrical activity begins in a local brain area and propagates before terminating. In a recent study, Liou and colleagues used multiscale computational modeling to gain mechanistic insights into clinical seizure dynamics based on cellular-level biophysical properties.

Indexed as

EpilepsyEpilepsy, GeneralizedBrainHumansModels, NeurologicalSeizurescomputational modelingepilepsyexcitationGABAinhibitionseizure dynamics

Identifiers

PMID32376035
PMCPMC7665900
OpenAlexW3023627512

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.