Evidence map›Paper›PMID 32375993›Full record

ArticleThe Journal of general virology2020

Basic insights into Zika virus infection of neuroglial and brain endothelial cells.

Margit Mutso, James A St John, Zheng Lung Ling, Felicity J Burt, Yee Suan Poo, Xiang Liu, Eva Žusinaite, Georges E Grau, Linda Hueston, Andres Merits and 3 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in The Journal of general virology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Review
  2. Impact of Tick-BorneInternational journal of molecular sciences · 2025
    Article
  3. Article
  4. Review
  5. Blood-Brain Barrier Breakdown in Neuroinflammation: Current In Vitro Models.International journal of molecular sciences · 2023
    Review
  6. Article
  7. Article
  8. Article
  9. Review
  10. Article
  11. Non-permissive SARS-CoV-2 infection in human neurospheres.bioRxiv : the preprint server for biology · 2021
    Article
  12. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Margit MutsoInstitute for Glycomics, Griffith University, Gold Coast Campus, Southport 4222, Queensland, Australia.
James A St JohnInstitute for Glycomics, Griffith University, Gold Coast Campus, Southport 4222, Queensland, Australia.
Zheng Lung LingDiscipline of Pathology, Bosch Institute, Marie Bashir Institute for Infectious diseases and Biosecurity, School of Medical Sciences, Sydney Medical School, University of Sydney, NSW 2006, Australia.
Felicity J BurtNational Health Laboratory Services, University of the Free State, Bloemfontein, South Africa.
Yee Suan PooInstitute for Glycomics, Griffith University, Gold Coast Campus, Southport 4222, Queensland, Australia.
Xiang LiuInstitute for Glycomics, Griffith University, Gold Coast Campus, Southport 4222, Queensland, Australia.
Eva ŽusinaiteInstitute of Technology, University of Tartu, Tartu, Estonia.
Georges E GrauVascular Immunology Unit, Discipline of Pathology, Sydney Medical School, University of Sydney, New South Wales 2050, Australia.
Linda HuestonArbovirus Emerging Disease Unit, CIDMLS-ICPMR, Westmead Hospital, Westmead, NSW 2145, Australia.
Andres MeritsInstitute of Technology, University of Tartu, Tartu, Estonia.
Nicholas J C KingDiscipline of Pathology, Bosch Institute, Marie Bashir Institute for Infectious diseases and Biosecurity, School of Medical Sciences, Sydney Medical School, University of Sydney, NSW 2006, Australia.
Jenny A K EkbergMenzies Health Institute Queensland, Griffith University, Gold Coast Campus, Southport 4222, Queensland, Australia.
Suresh MahalingamInstitute for Glycomics, Griffith University, Gold Coast Campus, Southport 4222, Queensland, Australia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Zika virus (ZIKV) has recently emerged as an important human pathogen due to the strong evidence that it causes disease of the central nervous system, particularly microcephaly and Guillain-Barré syndrome. The pathogenesis of disease, including mechanisms of neuroinvasion, may include both invasion via the blood-brain barrier and via peripheral (including cranial) nerves. Cellular responses to infection are also poorly understood. This study characterizes the

Indexed as

AnimalsBlood-Brain BarrierBrainCell LineChlorocebus aethiopsEndoplasmic ReticulumEndothelial CellsHumansMiceNeurogliaVero CellsVirus ReplicationZika VirusZika Virus Infectionendothelial cellsinfectivityneural cellsreplication kineticsZika virus

Identifiers

PMID32375993
PMCPMC7414445

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.