Evidence map›Paper›PMID 32375862›Full record

ArticleParasites & vectors2020

Impact of deltamethrin selection on kdr mutations and insecticide detoxifying enzymes in Aedes aegypti from Mexico.

Yamili Contreras-Perera, Gustavo Ponce-Garcia, Karina Villanueva-Segura, Beatriz Lopez-Monroy, Iram P Rodríguez-Sanchez, Audrey Lenhart, Pablo Manrique-Saide, Adriana E Flores

Open access · goldAbstract read
In one paragraph

Article in Parasites & vectors, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.3field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 33 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 2 countries.

Yamili Contreras-PereraFacultad de Ciencias Biologicas, Universidad Autonoma de Nuevo Leon, Cd, Universitaria, San Nicolas de los Garza, N.L., CP. 66455, Mexico.
Gustavo Ponce-GarciaFacultad de Ciencias Biologicas, Universidad Autonoma de Nuevo Leon, Cd, Universitaria, San Nicolas de los Garza, N.L., CP. 66455, Mexico.
Karina Villanueva-SeguraFacultad de Ciencias Biologicas, Universidad Autonoma de Nuevo Leon, Cd, Universitaria, San Nicolas de los Garza, N.L., CP. 66455, Mexico.
Beatriz Lopez-MonroyFacultad de Ciencias Biologicas, Universidad Autonoma de Nuevo Leon, Cd, Universitaria, San Nicolas de los Garza, N.L., CP. 66455, Mexico.
Iram P Rodríguez-SanchezFacultad de Ciencias Biologicas, Universidad Autonoma de Nuevo Leon, Cd, Universitaria, San Nicolas de los Garza, N.L., CP. 66455, Mexico.
Audrey LenhartDivision of Parasitic Diseases and Malaria, Centers for Disease Control and Prevention, Atlanta, GA, USA.
Pablo Manrique-SaideUnidad Colaborativa para Bioensayos Entomologicos, Universidad Autonoma de Yucatan, Campus de Ciencias Biologicas y Agropecuarias, Merida, Yucatan, Mexico.
Adriana E FloresFacultad de Ciencias Biologicas, Universidad Autonoma de Nuevo Leon, Cd, Universitaria, San Nicolas de los Garza, N.L., CP. 66455, Mexico. adriana.floressr@uanl.edu.mx.ORCID http://orcid.org/0000-0001-8554-8865
Universidad Autónoma de Nuevo León · MXAutonomous University of Yucatán · MXCenters for Disease Control and Prevention · US

Funding

CONACYT PN2016-2134.
6 · The paper itself

Abstract

backgroundInsecticide resistance is a serious problem for vector control programmes worldwide. Resistance is commonly attributed to mutations at the insecticide's target site or increased activity of detoxification enzymes.

methodsWe determined the knockdown concentration (KC

resultsThere was an increase in KC

conclusionsThe high levels of resistance and their association with high frequencies of kdr mutations (V410L, V1016I and F1534C) obtained through artificial selection, suggest an important role of these mutations in conferring resistance to deltamethrin. We highlight the need to implement strategies that involve the monitoring of kdr frequencies in insecticide resistance monitoring and management programmes.

Indexed as

AedesAnimalsEsterasesGenes, InsectGlutathione TransferaseInsect ControlInsecticide ResistanceInsecticidesMosquito VectorsMutationNitrilesOxidoreductasesPyrethrinsVascular Endothelial Growth Factor Receptor-2decamethrinEsterasesGlutathione TransferaseInsecticidesNitrilesOxidoreductasesPyrethrinsVascular Endothelial Growth Factor Receptor-2Aedes aegyptiF1534CHeritabilitykdr mutationsMetabolic detoxificationV1016IV410L

Identifiers

PMID32375862
PMCPMC7201803
OpenAlexW3023109461

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.