Evidence map›Paper›PMID 32375675›Full record

Observational studyBMC gastroenterology2020

Colonic transendoscopic tube-delivered enteral therapy (with video): a prospective study.

Ting Zhang, Chuyan Long, Bota Cui, Heena Buch, Quan Wen, Qianqian Li, Xiao Ding, Guozhong Ji, Faming Zhang

Open access · goldAbstract readObservational StudyVideo-Audio Media
In one paragraph

Observational study in BMC gastroenterology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
0.5field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 37 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Ting ZhangMedical Center for Digestive Diseases, the Second Affiliated Hospital of Nanjing Medical University, Nanjing, 210011, China.
Chuyan LongMedical Center for Digestive Diseases, the Second Affiliated Hospital of Nanjing Medical University, Nanjing, 210011, China.
Bota CuiMedical Center for Digestive Diseases, the Second Affiliated Hospital of Nanjing Medical University, Nanjing, 210011, China.
Heena BuchMedical Center for Digestive Diseases, the Second Affiliated Hospital of Nanjing Medical University, Nanjing, 210011, China.
Quan WenMedical Center for Digestive Diseases, the Second Affiliated Hospital of Nanjing Medical University, Nanjing, 210011, China.
Qianqian LiMedical Center for Digestive Diseases, the Second Affiliated Hospital of Nanjing Medical University, Nanjing, 210011, China.
Xiao DingMedical Center for Digestive Diseases, the Second Affiliated Hospital of Nanjing Medical University, Nanjing, 210011, China.
Guozhong JiMedical Center for Digestive Diseases, the Second Affiliated Hospital of Nanjing Medical University, Nanjing, 210011, China.
Faming ZhangMedical Center for Digestive Diseases, the Second Affiliated Hospital of Nanjing Medical University, Nanjing, 210011, China. fzhang@njmu.edu.cn.ORCID https://orcid.org/0000-0003-4157-1144
Second Affiliated Hospital of Nanjing Medical University · CNNanchang University · CNNanjing University of Chinese Medicine · CN

Funding

Jiangsu Province Creation Team and Leading Talents project -National Natural Science Foundation of China 81600417National Natural Science Foundation of China 81670495public donated Intestine Initiative Foundation -Top-notch Talent Research Projects LGY2017080
6 · The paper itself

Abstract

backgroundColonic transendoscopic enteral tubing (TET) refers to colonic transendoscopic tube-delivered enteral therapy. Colonic TET has been successfully used for frequent colonic administration of drugs or multiple fecal microbiota transplantations (FMTs). This prospective observational study aimed to evaluate possible factors affecting methodology, feasibility and safety of colonic TET.

methodsPatients who underwent colonic TET at our center from October 2014 to November 2018 were included. The feasibility, efficacy, and safety of TET were evaluated.

resultsIn total, 224 patients were analyzed. The success rate of TET was 100%. The median retention time of TET tube within the colonic lumen was 8.5 (IQR 7-11) days in 158 patients with tube falling out spontaneously, and the maximum retention time was up to 28 days. These patients were divided into the short-retention group (≤ 8.5 days) and the long-retention group (> 8.5 days). Univariate and multivariate analysis demonstrated that the type of endoscopic clip (p = 0.001) was an independent factor for the retention time. The larger clips as well as a greater number of clips significantly affected the retention time (p = 0.013). No severe adverse event was observed during and after TET.

conclusionsColonic TET is a feasible, practical, and safe colon-targeted drug delivery technique with a high degree of patients' satisfaction. Two to four large endoscopic clips are recommended to maintain stability of the TET tube within the colon for over 7 days.

Indexed as

Infusion Pumps, ImplantableAdultColitis, UlcerativeColonoscopyConstipationFeasibility StudiesFecal Microbiota TransplantationFemaleGastrointestinal AgentsHumansIntestinal DiseasesIntubation, GastrointestinalMaleMiddle AgedPatient SatisfactionProspective StudiesGastrointestinal AgentsColonoscopyEnemaFecal microbiota transplantationMethodTransendoscopic enteral tubing

Identifiers

PMID32375675
PMCPMC7203978
OpenAlexW3022088642

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.