ArticleThe journal of headache and pain2020
Predictors of pain in general ageing populations: results from a multi-country analysis based on ATHLOS harmonized database.
Article in The journal of headache and pain, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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13 citing papers in PubMed, 22 citations in OpenAlex.
- Assessment of depression and pain in the general population: a scoping review.BMC psychiatry · 2026Article
- Chronic pain in older adults with chronic diseases: prevalence, perceived interference, and management strategies.BMC geriatrics · 2025Article
- Sigma‑2 Receptor/Transmembrane Protein 97 in Pain Modulation: Tracing Historical Roots and Current Research Directions.ACS pharmacology & translational science · 2025Review
- Where Does It Hurt? A 4-S Model of Pain Onset and Recovery Across Body Sites Among Older Adults.The journals of gerontology. Series B, Psychological sciences and social sciences · 2025Article
- Large-Scale Plasma Proteomics to Profile Pathways and Prognosis of Chronic Pain.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025Article
- The World Health Organization Intersectoral Global Action Plan on Epilepsy and Other Neurological Disorders and the headache revolution: from headache burden to a global action plan for headache disorders.The journal of headache and pain · 2024Review
- Article
- Lifetime impact of achondroplasia study in Europe (LIAISE): findings from a multinational observational study.Orphanet journal of rare diseases · 2023Observational
- A Cross-Sectional and Longitudinal Study of Pain among Middle-Aged and Older Adults in Thailand.Pain research & management · 2023Article
- Investigating Prescription Medication Expenditures and Level of Perceived Health Status among Older Adults with Pain in the United States.Medicines (Basel, Switzerland) · 2022Article
- Patterns of Healthcare Expenditures among Older United States Adults with Pain and Different Perceived Health Status.Healthcare (Basel, Switzerland) · 2021Article
- Prevalence and Factors Associated With Body Pain: Results of a Nationally Representative Survey of 9,586 Chinese Adults Aged 60 and Over.Frontiers in public health · 2021Article
- Assessment of opioid administration patterns following lower extremity fracture among opioid-naïve inpatients: retrospective multicenter cohort study.Annals of Saudi medicineArticle
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Authors and funding
18 authors at 12 institutions in 9 countries.
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Abstract
backgroundPain is a common symptom, often associated with neurological and musculoskeletal conditions, and experienced especially by females and by older people, and with increasing trends in general populations. Different risk factors for pain have been identified, but generally from studies with limited samples and a limited number of candidate predictors. The aim of this study is to evaluate the predictors of pain from a large set of variables and respondents.
methodsWe used part of the harmonized dataset of ATHLOS project, selecting studies and waves with a longitudinal course, and in which pain was absent at baseline and with no missing at follow-up. Predictors were selected based on missing distribution and univariable association with pain, and were selected from the following domains: Socio-demographic and economic characteristics, Lifestyle and health behaviours, Health status and functional limitations, Diseases, Physical measures, Cognition, personality and other psychological measures, and Social environment. Hierarchical logistic regression models were then applied to identify significant predictors.
resultsA total of 13,545 subjects were included of whom 5348 (39.5%) developed pain between baseline and the average 5.2 years' follow-up. Baseline risk factors for pain were female gender (OR 1.34), engaging in vigorous exercise (OR 2.51), being obese (OR 1.36) and suffering from the loss of a close person (OR 1.88) whereas follow-up risk factors were low energy levels/fatigue (1.93), difficulties with walking (1.69), self-rated health referred as poor (OR 2.20) or average to moderate (OR 1.57) and presence of sleep problems (1.80).
conclusionsOur results showed that 39.5% of respondents developed pain over a five-year follow-up period, that there are proximal and distal risk factors for pain, and that part of them are directly modifiable. Actions aimed at improving sleep, reducing weight among obese people and treating fatigue would positively impact on pain onset, and avoiding vigorous exercise should be advised to people aged 60 or over, in particular if female or obese.
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