Evidence map›Paper›PMID 32375588›Full record

ArticleBioengineered2020

miR-211 alleviates ischaemia/reperfusion-induced kidney injury by targeting TGFβR2/TGF-β/SMAD3 pathway.

Jinchun Shang, Shukai Sun, Lin Zhang, Fengyun Hao, Dianlong Zhang

Open access · goldAbstract read
In one paragraph

Article in Bioengineered, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
1.8field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 34 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Jinchun ShangDepartment of Nephrology, The Affiliated Hospital of Qingdao University, Qingdao, Shandong, China.
Shukai SunDepartment of Clinical Lab, The Affiliated Hospital of Qingdao University, Qingdao, Shandong, China.
Lin ZhangDepartment of Anesthesia, The Affiliated Hospital of Qingdao University, Qingdao, Shandong, China.
Fengyun HaoDepartment of Pathology, The Affiliated Hospital of Qingdao University, Qingdao, Shandong, China.
Dianlong ZhangDepartment of Anesthesia, The Affiliated Hospital of Qingdao University, Qingdao, Shandong, China.ORCID 0000-0003-2131-9814
Qingdao University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

MicroRNA-211 (miR-211) is closely related to apoptosis and plays an important role in ischemia/reperfusion (I/R) injury. Whether miR-211 is involved in the protective effects in renal I/R injury is unknown. In this study, we evaluated the role of miR-211 in human tubular epithelial cells in response to hypoxia-reoxygenation (H/R) stimulation and I/R injury

Indexed as

AnimalsApoptosisBlotting, WesternCell LineCell SurvivalFemaleHumansIn Situ Nick-End LabelingMiceMicroRNAsRatsReal-Time Polymerase Chain ReactionReperfusion InjuryRNA, Small InterferingSmad3 ProteinTransforming Growth Factor betaMicroRNAsMIRN211 microRNA, humanMirn211 microRNA, mouseRNA, Small InterferingSmad3 ProteinTransforming Growth Factor betaacute kidney injuryHypoxia/reoxygenationischaemia/reperfusionmicrornamicrorna-211TGF-β

Identifiers

PMID32375588
PMCPMC8291827
OpenAlexW3023806539

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.