Evidence map›Paper›PMID 32375489›Full record

ArticleAmerican journal of rhinology & allergy2020

Computed Tomography Findings Can Help Identify Different Chronic Rhinosinusitis With Nasal Polyp Phenotypes.

Lauren T Roland, Sonya Marcus, Joseph S Schertzer, Sarah K Wise, Joshua M Levy, John M DelGaudio

Open access · greenAbstract read
In one paragraph

Article in American journal of rhinology & allergy, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
2.6field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it, 25 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Inflammatory characteristics of central compartment atopic disease.International forum of allergy & rhinology · 2023
    Article
  9. A Prospective Analysis of Systemic and Local Aeroallergen Sensitivity in Central Compartment Atopic Disease.Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery · 2022
    Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Lauren T RolandDepartment of Otolaryngology-Head and Neck Surgery, University of California, San Francisco, San Francisco, California.ORCID https://orcid.org/0000-0003-2036-7611
Sonya MarcusDivision of Otolaryngology-Head and Neck Surgery, Stony Brook University, Stony Brook, New York.
Joseph S SchertzerEmory School of Medicine, Atlanta, Georgia.ORCID https://orcid.org/0000-0002-4466-5923
Sarah K WiseDepartment of Otolaryngology-Head and Neck Surgery, Emory University, Atlanta, Georgia.
Joshua M LevyDepartment of Otolaryngology-Head and Neck Surgery, Emory University, Atlanta, Georgia.ORCID https://orcid.org/0000-0001-5907-3421
John M DelGaudioDepartment of Otolaryngology-Head and Neck Surgery, Emory University, Atlanta, Georgia.
Emory University · USStony Brook University · USUniversity of California, San Francisco · US

Funding

Implementing a Maternal health and PRegnancy Outcomes Vision for Everyone (IMPROVE)UL1TR002378 · NCATS · EMORY UNIVERSITY · PI Andres J Garcia, Elizabeth O. Ofili · 2017 to 2026
$92.1M
NCATS NIH HHS UL1 TR002378
6 · The paper itself

Abstract

backgroundChronic rhinosinusitis with nasal polyps (CRSwNPs) has several phenotypes.

objectivesThe goal of this study was to evaluate computed tomography (CT) findings associated with each CRSwNP phenotype.

methodsPatient charts between January 2015 and March 2019 were retrospectively reviewed. Patient groups, including allergic fungal rhinosinusitis (AFRS), aspirin-exacerbated respiratory disease (AERD), central compartment atopic disease (CCAD) and CRSwNP not otherwise specified (CRSwNP NOS), were determined by standard criteria. The oldest CT scan available was reviewed for Lund-Mackay (LM) score, septal involvement of inflammatory disease, opacification of olfactory clefts, nasal cavity opacification, and oblique positioning of the middle turbinates. Nonparametric analyses of variance were performed with correction for multiple comparisons.

resultsA total of 356 patients had scans available for review; 80 (23%) patients were categorized into the AFRS group, 101 (28%) in the AERD group, 43 (12%) in the CCAD group, and 132 (37%) in the CRSwNP NOS group. Septal inflammatory involvement and oblique middle turbinate orientation on CT scans was higher in both AERD patients and CCAD patients as compared to AFRS and CRSwNP NOS patients (

conclusionCRSwNP encompasses many subsets of disease, which have varying treatments and intraoperative findings. Preoperative CT findings can be used to differentiate between these groups to improve prediction of diagnoses and patient counseling.

Indexed as

Nasal PolypsRhinitisChronic DiseaseHumansPhenotypeRetrospective StudiesTomography, X-Ray Computedallergic fungal rhinosinusitisaspirin-exacerbated respiratory diseasecentral compartment atopic diseasechronic rhinosinusitis with nasal polypcomputed tomographyphenotype

Identifiers

PMID32375489
PMCPMC9630721
OpenAlexW3022362405

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.