Evidence map›Paper›PMID 32375411›Full record

ArticleViruses2020

Genomic Analyses of Potential Novel Recombinant Human Adenovirus C in Brazil.

Roozbeh Tahmasebi, Antonio Charlys da Costa, Kaelan Tardy, Rory J Tinker, Flavio Augusto de Padua Milagres, Rafael Brustulin, Maria da Aparecida Rodrigues Teles, Rogério Togisaki das Chagas, Cassia Vitória de Deus Alves Soares, Aripuana Sakurada Aranha Watanabe and 7 more

Open access · goldAbstract read
In one paragraph

Article in Viruses, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.2field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
  2. Article
  3. Development and validation of a multi-platform LAMP system for rapid HAdV-3 and HAdV-7 detection.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2025
    Article
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  6. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 7 institutions in 3 countries.

Roozbeh TahmasebiPolytechnic School of University of Sao Paulo, Sao Paulo 01246-903, Brazil.ORCID 0000-0001-9631-5530
Antonio Charlys da CostaInstitute of Tropical Medicine, University of Sao Paulo, Sao Paulo 01246-903, Brazil.ORCID 0000-0001-5516-5177
Kaelan TardyInstitute of Tropical Medicine, University of Sao Paulo, Sao Paulo 01246-903, Brazil.
Rory J TinkerFaculty of Biology, Medicine and Health, University of Manchester, Manchester M13 9PL, UK.
Flavio Augusto de Padua MilagresLIM/46, Faculty of Medicine, University of Sao Paulo, Sao Paulo 01246-903, Brazil.
Rafael BrustulinLIM/46, Faculty of Medicine, University of Sao Paulo, Sao Paulo 01246-903, Brazil.
Maria da Aparecida Rodrigues TelesSecretary of Health of Tocantins, Tocantins 77453-000, Brazil.
Rogério Togisaki das ChagasSecretary of Health of Tocantins, Tocantins 77453-000, Brazil.
Cassia Vitória de Deus Alves SoaresSecretary of Health of Tocantins, Tocantins 77453-000, Brazil.
Aripuana Sakurada Aranha WatanabeDepartment of Parasitology, Microbiology and Immunology, Federal University of Juiz de Fora, Juiz de Fora MG 34092829, Brazil.
Cecilia Salete AlencarCentral Laboratory Division-DLC-HCSP, Clinical Laboratory and LIM 03-Department of Pathology, Clinical Hospital, University of Sao Paulo Medical School, Sao Paulo 01246-000, Brazil.
Fabiola VillanovaInstitute of Biological Sciences, Federal University of Para, Para 66075-000, Brazil.
Xutao DengVitalant Research Institute, 270 Masonic Avenue, San Francisco, CA 94118-4417, USA.
Eric DelwartVitalant Research Institute, 270 Masonic Avenue, San Francisco, CA 94118-4417, USA.
Adriana LuchsEnteric Disease Laboratory, Virology Center, Adolfo Lutz Institute, Sao Paulo 01246-000, Brazil.
Élcio LealInstitute of Biological Sciences, Federal University of Para, Para 66075-000, Brazil.ORCID 0000-0003-3463-0492
Ester Cerdeira SabinoPolytechnic School of University of Sao Paulo, Sao Paulo 01246-903, Brazil.
Universidade de São Paulo · BRUniversidade do Tocantins · BRUniversidade Federal do Pará · BRUniversity of California, San Francisco · USInstituto Adolfo Lutz · BRUniversidade Federal de Juiz de Fora · BRUniversity of Manchester · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Human Adenovirus species C (HAdV-C) is the most common etiologic agent of respiratory disease. In the present study, we characterized the nearly full-length genome of one potential new HAdV-C recombinant strain constituted by Penton and Fiber proteins belonging to type 89 and a chimeric Hexon protein of types 1 and 89. By using viral metagenomics techniques, we screened out, in the states of Tocantins and Pará, Northern and North regions of Brazil, from 2010 to 2016, 251 fecal samples of children between 0.5 to 2.5 years old. These children were presenting acute diarrhea not associated with common pathogens (i.e., rotavirus, norovirus). We identified two HAdV-C strains in two distinct patients. Phylogenetic analysis performed using all complete genomes available at GenBank database indicated that one strain (HAdV-C BR-245) belonged to type 1. The phylogenetic analysis also indicated that the second strain (HAdV-C BR-211) was located at the base of the clade formed by the newly HAdV-C strains type 89. Recombination analysis revealed that strain HAdV-C BR-211 is a chimera in which the variable regions of

Indexed as

Genome, ViralAdenoviruses, HumanAdenovirus Infections, HumanAmino Acid SequenceBrazilCapsid ProteinsEvolution, MolecularGenomicsPhylogenyRecombination, GeneticCapsid ProteinsAdenovirus CGastroenteritisPhylogeneticsRecombinationVirome

Identifiers

PMID32375411
PMCPMC7290489
OpenAlexW3023064485

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.