Evidence map›Paper›PMID 32375387›Full record

ArticleToxins2020

Cnf1 Variants Endowed with the Ability to Cross the Blood-Brain Barrier: A New Potential Therapeutic Strategy for Glioblastoma.

Andrea Colarusso, Zaira Maroccia, Ermenegilda Parrilli, Elena Angela Pia Germinario, Andrea Fortuna, Stefano Loizzo, Laura Ricceri, Maria Luisa Tutino, Carla Fiorentini, Alessia Fabbri

Open access · goldAbstract readComparative Study
PubMed Full text at PMC Publisher
In one paragraph

Article in Toxins, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.3field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Bacteria associated with glioma: a next wave in cancer treatment.Frontiers in cellular and infection microbiology · 2023
    Review
  5. Article
  6. Review
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Andrea ColarussoDepartment of Chemical Sciences, University of Naples Federico II, Complesso Universitario M. S. Angelo, Via Cintia, 80126 Napoli, Italy.
Zaira MarocciaIstituto Superiore di Sanità, Viale Regina Elena 299, 00161 Rome, Italy.
Ermenegilda ParrilliDepartment of Chemical Sciences, University of Naples Federico II, Complesso Universitario M. S. Angelo, Via Cintia, 80126 Napoli, Italy.ORCID 0000-0002-9002-5409
Elena Angela Pia GerminarioIstituto Superiore di Sanità, Viale Regina Elena 299, 00161 Rome, Italy.
Andrea FortunaIstituto Superiore di Sanità, Viale Regina Elena 299, 00161 Rome, Italy.
Stefano LoizzoIstituto Superiore di Sanità, Viale Regina Elena 299, 00161 Rome, Italy.
Laura RicceriIstituto Superiore di Sanità, Viale Regina Elena 299, 00161 Rome, Italy.
Maria Luisa TutinoDepartment of Chemical Sciences, University of Naples Federico II, Complesso Universitario M. S. Angelo, Via Cintia, 80126 Napoli, Italy.ORCID 0000-0002-4978-6839
Carla FiorentiniIstituto Superiore di Sanità, Viale Regina Elena 299, 00161 Rome, Italy.ORCID 0000-0003-1707-6282
Alessia FabbriIstituto Superiore di Sanità, Viale Regina Elena 299, 00161 Rome, Italy.ORCID 0000-0002-3075-3367
Istituto Superiore di Sanità · ITUniversity of Naples Federico II · IT

Funding

La fabbrica dei sogni 2 - New developments for Rett syndrome ---
6 · The paper itself

Abstract

Among gliomas, primary tumors originating from glial cells, glioblastoma (GBM) identified as WHO grade IV glioma, is the most common and aggressive malignant brain tumor. We have previously shown that the

Indexed as

Capillary PermeabilityAnimalsAntineoplastic AgentsBacterial ToxinsBlood-Brain BarrierBrain NeoplasmsCell Line, TumorCell ProliferationEscherichia coli ProteinsGlioblastomaHumansMaleMice, Inbred C57BLSignal TransductionAntineoplastic AgentsBacterial Toxinscytotoxic necrotizing factor type 1Escherichia coli Proteinscytotoxic necrotizing factor type 1drug discoveryglioblastomaprotein purificationrecombinant protein production

Identifiers

PMID32375387
PMCPMC7290510
OpenAlexW3022054260

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.