Evidence map›Paper›PMID 32375360›Full record

ArticleJournal of clinical medicine2020

Ovarian Cancer in the Elderly: Time to Move towards a More Logical Approach to Improve Prognosis-A Study from the FRANCOGYN Group.

Ludivine Dion, Camille Mimoun, Krystel Nyangoh Timoh, Sofiane Bendifallah, Alexandre Bricou, Pierre Collinet, Cyril Touboul, Lobna Ouldamer, Henri Azaïs, Yohann Dabi and 18 more

Open access · goldAbstract read
In one paragraph

Article in Journal of clinical medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 1 pooled it
4.0field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 1 synthesis or guideline pooled it, 28 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Frailty and Cancer Prognosis.Current oncology reports · 2024
    Review
  5. Observational
  6. Post-operative residual disease and number of cycles of neoadjuvant chemotherapy in advanced epithelial ovarian carcinoma.International journal of gynecological cancer : official journal of the International Gynecological Cancer Society · 2023
    Article
  7. Observational
  8. Article
  9. Ovarian cancer in the older patient: where are we now? What to do next?Therapeutic advances in medical oncology · 2023
    Review
  10. Article
  11. Ovarian Cancer: Latest Advances and Prospects.Journal of clinical medicine · 2021
    Article
  12. Article
  13. Article
  14. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

28 authors at 15 institutions in 1 country.

Ludivine DionDepartment of Gynecology, Rennes University Hospital, 35000 Rennes, France.ORCID 0000-0001-8914-5756
Camille MimounDepartment of Gynecology and Obstetrics, Lariboisiere Hospital, 750019 Paris, France.
Krystel Nyangoh TimohDepartment of Gynecology, Rennes University Hospital, 35000 Rennes, France.
Sofiane BendifallahService de Gynécologie, Hopital TENON, AP-HP, 75020 Paris, France.
Alexandre BricouService de Chirurgie Gynécologique, Hôpital Croix Saint Simon, 75000 Paris, France.
Pierre CollinetService de Gynécologie, Hôpital Jeanne de Flandres, 59000 Lille, France.
Cyril TouboulService de Gynécologie, Hopital TENON, AP-HP, 75020 Paris, France.
Lobna OuldamerService de Gynécologie, 37000 Tours, France.
Henri AzaïsService de Gynécologie, Hôpital La Pitié Salpétrière, 75012 Paris, France.
Yohann DabiService de Gynécologie Obstétrique, Centre Hospitalier Inter Communal de Créteil, 94000 Créteil, France.
Cherif AkladiosService de Gynécologie Obstétrique, CHU Hautepierre, 67000 Strasbourg, France.
Geoffroy CanlorbeService de Gynécologie, Hôpital La Pitié Salpétrière, 75012 Paris, France.
Pierre-Adrien BolzeService de Gynécologie Obstétrique, CHU Lyon Sud, 69000 Lyon, France.
Hélène CostazDépartement d'Oncologie Chirurgicale, Centre Georges François Leclerc, 21000 Dijon, France.
Mathieu MezzadriDepartment of Gynecology and Obstetrics, Lariboisiere Hospital, 750019 Paris, France.
Tristan GauthierService de Gynécologie Obstétrique, CHU de Limoges, 87000 Limoges, France.ORCID 0000-0002-9688-0385
Frederik KridelkaService de Chirurgie Oncologique et Gynécologique, 4000 Liège, Belgique.
Pauline ChauvetService de Gynécologie Obstétrique, CHU de Clermont Ferrand, 63000 Clermont Ferrand, France.
Nicolas BourdelService de Gynécologie Obstétrique, CHU de Clermont Ferrand, 63000 Clermont Ferrand, France.
Martin KoskasService de Gynécologie, Hôpital Bichat, APHP, 75018 Paris, France.
Xavier CarcopinoService de Gynécologie, Hôpital La Timone, APHM, 13000 Marseille, France.
Emilie RaimondService de Gynécologie, Hôpital Universitaire de Reims, 51000 Reims, France.
Olivier GraesslinService de Gynécologie, Hôpital Universitaire de Reims, 51000 Reims, France.
Lise LecointreService de Gynécologie Obstétrique, CHU Hautepierre, 67000 Strasbourg, France.ORCID 0000-0002-1241-3094
Marcos BallesterService de Chirurgie Gynécologique, Hôpital Croix Saint Simon, 75000 Paris, France.
Jean LevêqueDepartment of Gynecology, Rennes University Hospital, 35000 Rennes, France.
Cyrille HuchonDepartment of Gynecology and Obstetrics, Lariboisiere Hospital, 750019 Paris, France.
Vincent LavouéDepartment of Gynecology, Rennes University Hospital, 35000 Rennes, France.ORCID 0000-0002-4682-2806
Sorbonne Université · FRHôpital Lariboisière · FRInserm · FRCentre Hospitalier Universitaire de Clermont-Ferrand · FRCentre Hospitalier Universitaire de Reims · FRGroupe Hospitalier Diaconesses Croix Saint-Simon · FRHôpital d'Hautepierre · FRAssistance Publique – Hôpitaux de Paris · FRCentre Georges François Leclerc · FRCentre Hospitalier Universitaire de Limoges · FRCentre Hospitalier Universitaire de Rennes · FRHôpital de la Timone · FRHôpital Intercommunal de Créteil · FRHôpital Jeanne de Flandre · FRHôpital Lyon Sud · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND AND

objectiveElderly and/or frail women with ovarian cancer are often undertreated. The aim of the study is to compare the effects of age and frailty on surgical approaches, postoperative complications, and prognosis in elderly women with ovarian cancer.

methodsA retrospective multicenter study of women ≥70 years were treated for ovarian cancer at seven French university hospitals between 2007 and 2015.

resultsOf the 1119 women treated for ovarian cancer during the study period, 147 were ≥70 years and had complete data. Of these women, 65 were aged 70-74 years, and 82 were aged ≥75 years. Overall, 77% of the younger women (49/65) received optimal treatment compared with 51% (40/82) of the older women (

conclusionsSurgeons modify their approach to treating ovarian cancer in women ≥75 years probably to reduce immediate postoperative complications. The prognosis is significantly worse in patients with greater frailty. Improvements to the sequence of treatments administered, with priority given to neoadjuvant chemotherapy in patients with greater frailty, could help increase the number of women who receive optimal treatment and improve their prognosis.

Indexed as

chemotherapyelderlyfrailtyovarian cancersurgery

Identifiers

PMID32375360
PMCPMC7291201
OpenAlexW3023360011

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.