Evidence map›Paper›PMID 32375318›Full record

ArticleDiagnostics (Basel, Switzerland)2020

Vitamin D-Binding Protein (Gc-Globulin) in Acute Liver Failure in Children.

Alina Grama, Lucia Burac, Cornel Olimpiu Aldea, Bogdan Bulata, Dan Delean, Gabriel Samasca, Carmen Abrudan, Claudia Sirbe, Tudor Lucian Pop

Open access · goldAbstract read
In one paragraph

Article in Diagnostics (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.5field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 16 citations in OpenAlex.

  1. Trial
  2. Review
  3. Review
  4. Review
  5. Nutritional Support in Acute Liver Failure.Diseases (Basel, Switzerland) · 2022
    Review
  6. Article
  7. Review
  8. Article
  9. Review
  10. Article
  11. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Alina Grama2nd Paediatric Clinic, University of Medicine and Pharmacy "Iuliu Hatieganu", 400177 Cluj-Napoca, Romania.ORCID 0000-0001-7022-6345
Lucia Burac2nd Paediatric Clinic, University of Medicine and Pharmacy "Iuliu Hatieganu", 400177 Cluj-Napoca, Romania.
Cornel Olimpiu AldeaPaediatric Nephrology, Dialysis and Toxicology Clinic, Emergency Clinical Hospital for Children, 400177 Cluj-Napoca, Romania.
Bogdan BulataPaediatric Nephrology, Dialysis and Toxicology Clinic, Emergency Clinical Hospital for Children, 400177 Cluj-Napoca, Romania.
Dan DeleanPaediatric Nephrology, Dialysis and Toxicology Clinic, Emergency Clinical Hospital for Children, 400177 Cluj-Napoca, Romania.
Gabriel SamascaLaboratory of Medical Analysis, Emergency Clinical Hospital for Children, 400177 Cluj-Napoca, Romania.ORCID 0000-0002-7645-0716
Carmen AbrudanLaboratory of Medical Analysis, Emergency Clinical Hospital for Children, 400177 Cluj-Napoca, Romania.
Claudia Sirbe2nd Paediatric Clinic, University of Medicine and Pharmacy "Iuliu Hatieganu", 400177 Cluj-Napoca, Romania.
Tudor Lucian Pop2nd Paediatric Clinic, University of Medicine and Pharmacy "Iuliu Hatieganu", 400177 Cluj-Napoca, Romania.ORCID 0000-0002-4931-1219
Clinical Emergency Hospital Bucharest · ROIuliu Hațieganu University of Medicine and Pharmacy · ROCarol Davila University of Medicine and Pharmacy · RO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study aimed to analyse vitamin d-binding protein (Gc-globulin) serum levels in acute liver failure (ALF) in children in relation to disease outcomes and correlations with other known markers used to evaluate the severity of ALF. Our study included 34 children (mean age 4.87 ± 5.30 years) with ALF of different causes (metabolic, 26.47%; autoimmune, 23.53%; toxic, 20.59%; infection, 17.65%; unknown, 11.76%) and 30 children without any liver injury (mean age 6.11 ± 4.26 years). The outcome was poor in 14 patients (41.18%), including one child with liver transplantation (2.94%). Serum Gc-globulin levels were significantly lower in ALF patients compared to the control group (151.57 ± 171.8 mg/L vs. 498.63 ± 252.50 mg/L;

Indexed as

acute liver failurechildrenGc-globulinliver transplantmortalityprognostic markervitamin D binding protein

Identifiers

PMID32375318
PMCPMC7278011
OpenAlexW3022593717

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.