Evidence map›Paper›PMID 32375243›Full record

ArticleVaccines2020

HIV gp120 Induces the Release of Proinflammatory, Angiogenic, and Lymphangiogenic Factors from Human Lung Mast Cells.

Giancarlo Marone, Francesca Wanda Rossi, Antonio Pecoraro, Valentina Pucino, Gjada Criscuolo, Amato de Paulis, Giuseppe Spadaro, Gianni Marone, Gilda Varricchi

Open access · goldAbstract read
In one paragraph

Article in Vaccines, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
1.5field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 28 citations in OpenAlex.

  1. Article
  2. Role of HIV-encoded proteins in cardiovascular disease.American journal of physiology. Cell physiology · 2025
    Review
  3. Review
  4. Review
  5. Review
  6. Article
  7. Article
  8. Article
  9. Review
  10. Article
  11. Review
  12. Article
  13. Article
  14. Article
  15. Review
  16. Article
  17. Review
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 2 countries.

Giancarlo MaroneDepartment of Public Health, Section of Hygiene, University of Naples Federico II, 80138 Naples, Italy.
Francesca Wanda RossiDepartment of Translational Medical Sciences, University of Naples Federico II, 80138 Naples, Italy.
Antonio PecoraroDepartment of Translational Medical Sciences, University of Naples Federico II, 80138 Naples, Italy.
Valentina PucinoInstitute of Inflammation and Ageing, College of Medical and Dental Sciences, University of Birmingham, Birmingham B15 2TT, UK.
Gjada CriscuoloDepartment of Translational Medical Sciences, University of Naples Federico II, 80138 Naples, Italy.
Amato de PaulisDepartment of Translational Medical Sciences, University of Naples Federico II, 80138 Naples, Italy.
Giuseppe SpadaroDepartment of Translational Medical Sciences, University of Naples Federico II, 80138 Naples, Italy.
Gianni MaroneDepartment of Translational Medical Sciences, University of Naples Federico II, 80138 Naples, Italy.
Gilda VarricchiDepartment of Translational Medical Sciences, University of Naples Federico II, 80138 Naples, Italy.
Institute for Experimental Endocrinology and Oncology · ITWorld Health Organization - Italy · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Human lung mast cells (HLMCs) express the high-affinity receptor FcεRI for IgE and are involved in chronic pulmonary diseases occurring at high frequency among HIV-infected individuals. Immunoglobulin superantigens bind to the variable regions of either the heavy or light chain of immunoglobulins (Igs). Glycoprotein 120 (gp120) of HIV-1 is a typical immunoglobulin superantigen interacting with the heavy chain, variable 3 (V

Indexed as

angiogenesisgp120histamineHIVIgEleukotriene C4lymphangiogenesismast cellsprostaglandin D2superantigen

Identifiers

PMID32375243
PMCPMC7349869
OpenAlexW3023527735

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.