Evidence map›Paper›PMID 32375241›Full record

ReviewHigh-throughput2020

Microbiota and Human Reproduction: The Case of Female Infertility.

Rossella Tomaiuolo, Iolanda Veneruso, Federica Cariati, Valeria D'Argenio

Registry-linked trialOpen access · goldAbstract readReview
In one paragraph

Review in High-throughput, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05514223 (MeaSuring Free radIcals With Diamond magnetometrRy In hUman Single Sperm Cells Related to Microbiota and Lifestyle Factors), which is not on this map. Cited by 43 papers.

0numbers the graph read from it
0cells of the map it votes in
43citing papers in PubMed
8.5field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05514223 recruitingnot on this mapstarted 2024, after this paper: background citation

MeaSuring Free radIcals With Diamond magnetometrRy In hUman Single Sperm Cells Related to Microbiota and Lifestyle Factors

TypeobservationalSponsorUniversity Medical Center GroningenRan2024 to 2027Enrolled80ConditionsInfertility, Male, InfertilityArmsBiomaterial collection for observational purpose
3 · Its place in the literature

Who cites it

43 citing papers in PubMed, 106 citations in OpenAlex.

  1. Article
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  6. Review
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  14. Therapeutic potential of microbiome modulation in reproductive cancers.Medical oncology (Northwood, London, England) · 2025
    Review
  15. All Properties of Infertility Microbiome in a Review Article.Journal of clinical laboratory analysis · 2025
    Review
  16. Review
  17. Article
  18. Review
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Rossella TomaiuoloKronosDNA srl, Spinoff of Federico II University, 80133 Napoli, Italy.
Iolanda VenerusoDepartment of Molecular Medicine and Medical Biotechnologies, Federico II University, Via Sergio Pansini 5, 80131 Napoli, Italy.
Federica CariatiKronosDNA srl, Spinoff of Federico II University, 80133 Napoli, Italy.
Valeria D'ArgenioCEINGE-Biotecnologie Avanzate scarl, Via Gaetano Salvatore 486, 80145 Napoli, Italy.ORCID 0000-0001-9273-3698
Federico II University Hospital · ITSan Raffaele University of Rome · IT

Funding

EIT Health year 2016H2020 Innovation In SMEs 855720
6 · The paper itself

Abstract

During the last decade, the availability of next-generation sequencing-based approaches has revealed the presence of microbial communities in almost all the human body, including the reproductive tract. As for other body sites, this resident microbiota has been involved in the maintenance of a healthy status. As a consequence, alterations due to internal or external factors may lead to microbial dysbiosis and to the development of pathologies. Female reproductive microbiota has also been suggested to affect infertility, and it may play a key role in the success of assisted reproductive technologies, such as embryo implantation and pregnancy care. While the vaginal microbiota is well described, the uterine microbiota is underexplored. This could be due to technical issues, as the uterus is a low biomass environment. Here, we review the state of the art regarding the role of the female reproductive system microbiota in women's health and human reproduction, highlighting its contribution to infertility.

Indexed as

female infertilityfemale reproductive systemhuman microbiomehuman reproductionmicrobiota

Identifiers

PMID32375241
PMCPMC7349014
OpenAlexW3015261945

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.