Evidence map›Paper›PMID 32375150›Full record

ArticleCardiorenal medicine2020

Fulminant Acute Kidney Injury in a Young Patient with Novel Coronavirus 2019.

Akshaya Gopalakrishnan, Ali Mossaid, Kevin Bryan Lo, Viswanath Vasudevan, Peter A McCullough, Janani Rangaswami

Open access · bronzeAbstract readCase Reports
In one paragraph

Article in Cardiorenal medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 3 pooled it
0.6field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 3 syntheses or guidelines pooled it, 24 citations in OpenAlex.

  1. Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 1 country.

Akshaya GopalakrishnanDepartment of Medicine, The Brooklyn Hospital Center, Brooklyn, New York, USA, akshayamd92@gmail.com.
Ali MossaidDepartment of Medicine, The Brooklyn Hospital Center, Brooklyn, New York, USA.
Kevin Bryan LoDepartment of Medicine, Einstein Medical Center, Philadelphia, Pennsylvania, USA.
Viswanath VasudevanDepartment of Medicine, The Brooklyn Hospital Center, Brooklyn, New York, USA.
Peter A McCulloughBaylor University Medical Center, Baylor Heart and Vascular Hospital, Baylor Heart and Vascular Institute, Dallas, Texas, USA.
Janani RangaswamiDepartment of Medicine, Einstein Medical Center, Philadelphia, Pennsylvania, USA.
Brooklyn Hospital Center · USBaylor University Medical Center · USEinstein Medical Center Philadelphia · USThomas Jefferson University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Coronavirus disease 2019 (COVID-19) is a global pandemic affecting more than 200 countries and 180,000 cases in the United States. While the outbreak began in China, the number of cases outside of China exceeded those in China on March 15, 2020 and are currently rising at an exponential rate. The number of fatalities in the United States are expected to exceed more than Italy and China. The disease is characterized predominantly as an acute respiratory illness. However, preliminary data suggests that kidney is a target for the virus and deterioration of renal function was associated with poor outcomes including in-hospital mortality. We pre-sent a report of a patient with COVID-19 who presented with acute onset of symptoms and normal renal function at baseline but rapidly deteriorated resulting in death. The timing of decline in renal function correlated with his worsening clinical status. He was started on continuous veno-venous hemofiltration without signs of clinical benefit. We also present the possible mechanisms for acute kidney injury in these patients. We performed a review of the emerging literature by searching PubMed, Google Scholar, and EMBASE for studies and/or case series published on this topic. Acute kidney injury might help risk stratify critically ill patients on a fatal course of COVID-19.

Indexed as

BetacoronavirusAcute Kidney InjuryAdultCoronavirus InfectionsCOVID-19Fatal OutcomeHumansMalePandemicsPneumonia, ViralSARS-CoV-2ACE2 receptorsAcute kidney injuryContinuous veno-venous hemofiltrationCoronavirus disease 2019

Identifiers

PMID32375150
PMCPMC7251584
OpenAlexW3021816259

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.