ArticlePloS one2020
Clinical characteristics and long-term evolution of lamellar macular hole in high myopia.
Article in PloS one, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed, 24 citations in OpenAlex.
- Aberrant Functional Lateralization and Interhemispheric Synergy in High Myopia: Insights From Neurotransmitter Distribution Signatures and Machine Learning Classification.Investigative ophthalmology & visual science · 2026Article
- Axial length-based comparison of clinical characteristics and visual outcomes in macular pseudohole, epiretinal membrane foveoschisis, and lamellar macular hole.BMC ophthalmology · 2025Article
- Classification and management of myopic traction maculopathy: a vitrectomy-based consensus from taiwanese experts.International ophthalmology · 2025Article
- Incidence and risk factors of ocular complications among patients with homocystinuria in Saudi Arabia: a cross-sectional study.Annals of medicine and surgery (2012) · 2025Article
- Myopic traction maculopathy in fovea-involved myopic chorioretinal atrophy.Eye (London, England) · 2024Article
- Article
- Lamellar macular hole in highly myopic eyes and insights into its development, evolution, and treatment: a mini-review.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2024Review
- Multimodal Analysis on Clinical Characteristics of the Advanced Stage in Myopic Traction Maculopathy.Ophthalmology and therapy · 2023Article
- The development and evolution of lamellar macular hole in highly myopic eyes.Eye (London, England) · 2023Article
- The clinical and pathogenic significance of atypical epiretinal tissue in macular hole.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2022Review
- Combined fovea-sparing internal limiting membrane peeling with internal limiting membrane flap technique for progressive myopic traction maculopathy.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2022Observational
- Case report: Spontaneous bilateral intraocular lens dislocation in a patient with homocystinuria.Frontiers in cardiovascular medicine · 2022Article
- Complications of high myopia: An update from clinical manifestations to underlying mechanisms.Advances in ophthalmology practice and researchReview
- Surgical Management of Full-Thickness Macular Holes Spontaneously Arising From Lamellar Macular Holes.Journal of vitreoretinal diseasesArticle
Corrections and comments
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Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeTo evaluate the clinical characteristics and evolution of lamellar macular hole (LMH) in high myopia and the parameters associated with structural worsening, defined as the development of foveal detachment or full-thickness macular hole.
methodsPatients with high myopia and LMH were retrospectively recruited. The clinical characteristics and various parameters of optical coherence tomography were identified at baseline and during follow-up visits. Cox regression analysis was used to evaluate the hazard ratios for foveal detachment and full-thickness macular hole.
resultsAmong 112 eyes (98 patients), 64.3% were female; the mean axial length of all eyes was 29.6 ± 1.9 mm. The 'LMH without retinoschisis' group accounted for 39.3% of the eyes. Forty-two percent developed structural worsening within a median follow-up of 67 months. Multivariable regression on all cases showed elevated tissue inside the LMH (P = 0.003) protected against structural worsening while V-shaped LMH (P = 0.006) predicted it. In the "LMH with retinoschisis group", ellipsoid zone disruption (P = 0.035), and V-shaped LMH (P = 0.014) predicted structural worsening, while elevated tissue inside the LMH (P = 0.028) protected against it. In the "LMH without retinoschisis group", no associated factor was identified.
conclusionsLMHs in high myopia are unstable, especially those with V-shaped LMH. Elevated tissue inside LMHs have a protective effect against further structural worsening.
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