ArticlePloS one2020
Elicitation with Bacillus QV15 reveals a pivotal role of F3H on flavonoid metabolism improving adaptation to biotic stress in blackberry.
Article in PloS one, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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16 citing papers in PubMed, 27 citations in OpenAlex.
- miR156-StSPL9 regulating the biosynthesis of flavonoids and secondary metabolites in potato tubers.BMC plant biology · 2026Article
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- Copper Sulfate Elicitation Effect on Biomass Production, Phenolic Compounds Accumulation, and Antioxidant Activity ofPlants (Basel, Switzerland) · 2025Article
- The Crossregulation Triggered byPlants (Basel, Switzerland) · 2024Article
- Editorial: Women in microbe and virus interactions with plants: 2022/2023.Frontiers in microbiology · 2024Article
- Identification of Flavanone 3-Hydroxylase Gene Family in Strawberry and Expression Analysis of Fruit at Different Coloring Stages.International journal of molecular sciences · 2023Article
- Integrative Omic Analysis Reveals the Dynamic Change in Phenylpropanoid Metabolism inPlants (Basel, Switzerland) · 2023Article
- Flavonoids Are Intra- and Inter-Kingdom Modulator Signals.Microorganisms · 2022Review
- Modulation of Photosynthesis and ROS Scavenging Response by Beneficial Bacteria inPlants (Basel, Switzerland) · 2022Article
- Antioxidant, Anti-Inflammatory and Cytotoxic Activity of Phenolic Compound Family Extracted from Raspberries (Antioxidants (Basel, Switzerland) · 2022Review
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- Multi-Omics and miRNA Interaction Joint Analysis Highlight New Insights Into Anthocyanin Biosynthesis in Peanuts (Frontiers in plant science · 2022Article
- Transcriptomic and metabolomic joint analysis reveals distinct flavonoid biosynthesis regulation for variegated testa color development in peanut (Arachis hypogaea L.).Scientific reports · 2021Article
- Evaluation of the Cytotoxicity of Ayahuasca Beverages.Molecules (Basel, Switzerland) · 2020Article
- Ayahuasca Beverages: Phytochemical Analysis and Biological Properties.Antibiotics (Basel, Switzerland) · 2020Article
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The aim of this study is to determine the involvement of the flavonol-anthocyanin pathway on plant adaptation to biotic stress using the B.amyloliquefaciens QV15 to trigger blackberry metabolism and identify target genes to improve plant fitness and fruit quality. To achieve this goal, field-grown blackberries were root-inoculated with QV15 along its growth cycle. At fruiting, a transcriptomic analysis by RNA-Seq was performed on leaves and fruits of treated and non-treated field-grown blackberries after a sustained mildew outbreak; expression of the regulating and core genes of the Flavonol-Anthocyanin pathway were analysed by qPCR and metabolomic profiles by UHPLC/ESI-qTOF-MS; plant protection was found to be up to 88%. Overexpression of step-controlling genes in leaves and fruits, associated to lower concentration of flavonols and anthocyanins in QV15-treated plants, together with a higher protection suggest a phytoanticipin role for flavonols in blackberry; kempferol-3-O-rutinoside concentration was strikingly high. Overexpression of RuF3H (Flavonol-3-hidroxylase) suggests a pivotal role in the coordination of committing steps in this pathway, controlling carbon flux towards the different sinks. Furthermore, this C demand is supported by an activation of the photosynthetic machinery, and boosted by a coordinated control of ROS into a sub-lethal range, and associated to enhanced protection to biotic stress.
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