ReviewCancer2020
Posttraumatic stress disorder and breast cancer: Risk factors and the role of inflammation and endocrine function.
Review in Cancer, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 42 papers, 4 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
42 citing papers in PubMed, 4 syntheses or guidelines pooled it, 63 citations in OpenAlex.
- "Anxiety and worry" induces fear transformation in cancer patients: an evidence-based exploration and theoretical consideration of the emotional evolution in tumor patients.BMC psychology · 2025Pooled it
- The impact of mind-body exercise on female breast cancer patients-a systematic review and meta-analysis of randomized controlled trials.Frontiers in public health · 2025Pooled it
- A meta-analysis of the association between post-traumatic stress disorder and cancer risk.Frontiers in psychiatry · 2023Pooled it
- EMDR in Cancer Patients: A Systematic Review.Frontiers in psychology · 2020Pooled it
- The Effects of Light Therapy on Cognitive Function and Stress in Women With Breast Cancer Before Systemic Treatment.Cancer medicine · 2025Trial
- The effect of a group cognitive behavioral therapy on the quality of life and emotional disturbance of women with breast cancer.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2022Trial
- Patterns of sexual dysfunction among breast cancer survivors five years after diagnosis: a latent class analysis of the French VICAN5 study.Journal of cancer survivorship : research and practice · 2026Article
- Systems approach to integrative oncology in breast cancer care: service design, delivery and patient experiences from a UK center.Frontiers in oncology · 2026Article
- Unraveling Complex Interactions Mechanisms Linking PTSD and Chronic Diseases.Current neuropharmacology · 2026Review
- Cognitive Mechanisms Explaining the Relationship Between Post-Traumatic Stress and Post-Traumatic Growth in Survivors of Breast Cancer.Current oncology (Toronto, Ont.) · 2025Article
- Poorer Quality of Life Outcomes Are Associated with Higher Levels of Stress, Lower Levels of Resilience, and Poorer Adjustment to Cancer in Outpatients Receiving Chemotherapy.Seminars in oncology nursing · 2025Article
- Radiation effects research foundation-a view to the future.Carcinogenesis · 2025Article
- Impact of Socio-Demographic Factors, Financial Burden, and Social Support on Anxiety and Depression Symptoms in Puerto Rican Women with Breast Cancer.Behavioral sciences (Basel, Switzerland) · 2025Article
- Mental distress and inflammation in bladder cancer: The nerve makes things less vague.Brain, behavior, & immunity - health · 2025Article
- Article
- The influence of spirituality on psychological resilience in cancer patients undergoing oncological treatment: a cross-sectional study.BMC palliative care · 2025Observational
- Development and validation of a risk prediction model for post-traumatic stress disorder among Chinese breast cancer survivors.Scientific reports · 2025Article
- Global evolution of breast cancer incidence in childbearing-age women aged 15-49 years: a 30-year analysis.Journal of cancer research and clinical oncology · 2025Article
- Sex-stratified Genomic Structural Equation Models of Posttraumatic Stress Inform PTSD Etiology: L'utilisation de la modélisation génomique par équations structurelles stratifiée par sexe du stress post-traumatique pour expliquer l'étiologie du TSPT.Canadian journal of psychiatry. Revue canadienne de psychiatrie · 2025Article
- Prediction and Feature Selection of Mastectomy-Related Post Traumatic Stress Disorder (PTSD) Using Machine Learning Among Breast Cancer Patients in Bangladesh.Cancer informatics · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 2 institutions in 1 country.
Funding
Abstract
A breast cancer diagnosis can be a life-changing and stressful experience that can lead to chronic mental health conditions such as posttraumatic stress disorder (PTSD). Greater than one-third of patients initially diagnosed with PTSD after a diagnosis of breast cancer continue to have persistent or worsening PTSD symptoms after 4 years. An emerging body of literature has indicated several key environmental and biological risk factors for PTSD among survivors of breast cancer. Well-recognized risk factors include having a history of childhood trauma, being nonwhite, obesity, younger age at the time of diagnosis, diagnosis with a higher stage of breast cancer, and short time since treatment. Of the emerging risk factors related to fear circuitry in the brain, 2 pathways of particular importance are the stress-driven activation of inflammatory pathways and the long-term effect of antiendocrine therapies. These central and peripheral responses during and after stress exposure are important because increased fear and anxiety can lead to the maintenance of PTSD and worse patient outcomes. Given the poor outcomes associated with PTSD and the high prevalence of breast cancer in women, more research to identify those women at heightened risk of PTSD after breast cancer is warranted to reduce the number of diagnoses and lessen the negative impact of this chronic mental health condition.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.