ArticleJournal of neurophysiology2020
Motor cortical thickness is related to effort-based decision-making in humans.
Article in Journal of neurophysiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
9 citing papers in PubMed.
- Fatigue Symptoms Influence Effort-Based Decision-Making in Major Depressive Disorder.Biological psychiatry global open science · 2026Article
- Increased exertion variability is linked to disruptions in effort assessment in multiple sclerosis.Multiple sclerosis (Houndmills, Basingstoke, England) · 2026Article
- Shared and distinct features of common effort-based decision-making paradigms and their relation to brain structure and neuropsychiatric conditions: An integrated narrative review.Cognitive, affective & behavioral neuroscience · 2026Review
- Neural mechanisms underlying the effects of cognitive fatigue on physical effort-based choice.bioRxiv : the preprint server for biology · 2024Article
- Neurobiological foundations and clinical relevance of effort-based decision-making.Brain imaging and behavior · 2024Review
- Dopamine facilitates the translation of physical exertion into assessments of effort.NPJ Parkinson's disease · 2023Article
- Development and validation of a novel model based on hand knob score and white matter injury on MRI to predict hand function in children with cerebral palsy.Annals of translational medicine · 2022Article
- Sensorimotor Cortex GABA Moderates the Relationship between Physical Exertion and Assessments of Effort.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2022Article
- Effort-Based Decision-Making and Gross Motor Performance: Are They Linked?Brain sciences · 2020Article
Corrections and comments
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Authors and funding
5 authors.
Funding
Abstract
Although motor cortex is integral in driving physical exertion, how its inherent properties influence decisions to exert is unknown. In this study, we examined how anatomical properties of motor cortex are related to participants' subjective valuations of effort and their decisions to exert effort. We used computational modeling to characterize participants' subjective valuation of physical effort during an effort-based decision-making task in which they made choices about exerting different levels of hand-grip exertion. We also acquired structural MRI data from these participants and extracted anatomical measures of each individual's hand knob, the region of motor cortex recruited during hand-grip exertion. We found that individual participants' cortical thickness of hand knob was associated with their effort-based decisions regarding hand exertion. These data provide evidence that the anatomy of an individual's motor cortex is an important factor in decisions to engage in physical activity.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.