Evidence map›Paper›PMID 32374063›Full record

ArticleHuman brain mapping2020

In vivo characterization of emerging white matter microstructure in the fetal brain in the third trimester.

Camilo Jaimes, Fedel Machado-Rivas, Onur Afacan, Shadab Khan, Bahram Marami, Cynthia M Ortinau, Caitlin K Rollins, Clemente Velasco-Annis, Simon K Warfield, Ali Gholipour

Abstract read
In one paragraph

Article in Human brain mapping, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

32 citing papers in PubMed.

  1. Article
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  7. A detailed spatiotemporal atlas of the white matter tracts for the fetal brain.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  8. Article
  9. Article
  10. Article
  11. Advances in Fetal Brain Imaging.Magnetic resonance imaging clinics of North America · 2024
    Review
  12. Development of the Fetal Brain Corticocortical Structural Network during the Second-to-Third Trimester Based on Diffusion MRI.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2024
    Article
  13. Article
  14. Article
  15. Review
  16. Article
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  19. Article
  20. Fetal MRI at 3 T: Principles to Optimize Success.Radiographics : a review publication of the Radiological Society of North America, Inc · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Camilo JaimesDepartment of Radiology, Boston Children's Hospital, Boston, Massachusetts.ORCID 0000-0002-7169-4244
Fedel Machado-RivasDepartment of Radiology, Boston Children's Hospital, Boston, Massachusetts.ORCID 0000-0003-3095-414X
Onur AfacanDepartment of Radiology, Boston Children's Hospital, Boston, Massachusetts.ORCID 0000-0003-2112-3205
Shadab KhanDepartment of Radiology, Boston Children's Hospital, Boston, Massachusetts.
Bahram MaramiDepartment of Radiology, Boston Children's Hospital, Boston, Massachusetts.
Cynthia M OrtinauDepartment of Pediatrics, Washington University in St. Louis School of Medicine, St. Louis, Missouri.
Caitlin K RollinsHarvard Medical School, Boston, Massachusetts.
Clemente Velasco-AnnisDepartment of Radiology, Boston Children's Hospital, Boston, Massachusetts.
Simon K WarfieldDepartment of Radiology, Boston Children's Hospital, Boston, Massachusetts.
Ali GholipourDepartment of Radiology, Boston Children's Hospital, Boston, Massachusetts.

Funding

Mouse Neurodevelopmental Behavior CoreU54HD090255 · NICHD · BOSTON CHILDREN'S HOSPITAL · PI POMEROY, SCOTT LOREN · 2016 to 2020
$5.2M
Advancing Microstructural and Vascular Neuroimaging in Perinatal StrokeR01NS106030 · NINDS · BOSTON CHILDREN'S HOSPITAL · PI WARFIELD, SIMON K · 2019 to 2023
$1.7M
Motion-robust super-resolution diffusion weighted MRI of early brain developmentR01EB018988 · NIBIB · BOSTON CHILDREN'S HOSPITAL · PI GHOLIPOUR-BABOLI, ALI · 2014 to 2017
$1.6M
Fetal Brain Development in Congenital Heart DiseaseK23NS101120 · NINDS · BOSTON CHILDREN'S HOSPITAL · PI ROLLINS, CAITLIN · 2017 to 2022
$1.1M
Physiologic and Genetic Contributions of Impaired Fetal Brain Development in Congenital Heart DiseaseK23HL141602 · NHLBI · WASHINGTON UNIVERSITY · PI ORTINAU, CYNTHIA MARIE · 2019 to 2022
$727k
Fetal Health FoundationMcKnight FoundationNHLBI NIH HHS K23 HL141602NIBIB NIH HHS R01 EB018988NICHD NIH HHS U54 HD090255NINDS NIH HHS K23 NS101120NINDS NIH HHS R01 NS106030Schlaeger Fellowship for Neuroscience Research
6 · The paper itself

Abstract

The third trimester of pregnancy is a period of rapid development of fiber bundles in the fetal white matter. Using a recently developed motion-tracked slice-to-volume registration (MT-SVR) method, we aimed to quantify tract-specific developmental changes in apparent diffusion coefficient (ADC), fractional anisotropy (FA), and volume in third trimester healthy fetuses. To this end, we reconstructed diffusion tensor images from motion corrected fetal diffusion magnetic resonance imaging data. With an approved protocol, fetal MRI exams were performed on healthy pregnant women at 3 Tesla and included multiple (2-8) diffusion scans of the fetal head (1-2 b = 0 s/mm

Indexed as

Pregnancy Trimester, ThirdDiffusion Tensor ImagingFemaleFetal DevelopmentFetusHumansMaleNeural PathwaysPregnancyPrenatal DiagnosisWhite Matterdeveloping white matterdiffusion tensor imagingdiffusion weighted MRIfetal brainfetal MRItractographytract-specific analysiswhite matter microstructure

Identifiers

PMID32374063
PMCPMC7375105

What OpenQuestion holds

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LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.