ArticleOrigins of life and evolution of the biosphere : the journal of the International Society for the Study of the Origin of Life1988
The polymerization of amino acid adenylates on sodium-montmorillonite with preadsorbed polypeptides.
Article in Origins of life and evolution of the biosphere : the journal of the International Society for the Study of the Origin of Life, 1988. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed.
- Origins and emergent evolution of life: the colloid microsphere hypothesis revisited.Origins of life and evolution of the biosphere : the journal of the International Society for the Study of the Origin of Life · 2014Article
- Darwin's warm little pond revisited: from molecules to the origin of life.Die Naturwissenschaften · 2009Review
- The origin and emergence of life under impact bombardment.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2006Article
- The effect of smectite composition on the catalysis of peptide bond formation.Journal of molecular evolution · 1996Article
- Speculations on the origin of the genetic code.Journal of molecular evolution · 1995Review
- Catalysis and prebiotic RNA synthesis.Origins of life and evolution of the biosphere : the journal of the International Society for the Study of the Origin of Life · 1993Article
- Experimental studies on the origin of the genetic code and the process of protein synthesis: a review update.Origins of life and evolution of the biosphere : the journal of the International Society for the Study of the Origin of Life · 1992Review
- Growth of peptide chains on silica in absence of amino acid access from without.Origins of life and evolution of the biosphere : the journal of the International Society for the Study of the Origin of Life · 1991Article
- Chemical esterification of 5'-AMP occurs predominantly at the 2' position.Journal of molecular evolution · 1990Article
- Mineral catalysis of the formation of dimers of 5'-AMP in aqueous solution: the possible role of montmorillonite clays in the prebiotic synthesis of RNA.Origins of life and evolution of the biosphere : the journal of the International Society for the Study of the Origin of Life · 1989Article
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2 authors.
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Abstract
We studied the spontaneous polymerization of amino acid adenylates on Na-montmorillonite in dilute, neutral suspension, after polypeptides were adsorbed on the clay. This led to the unexpected finding that the degrees of polymerization (DP's) of the oligo- and poly-peptides obtained depended on the amounts of polypeptides that were preadsorbed. Plotting average molecular weights obtained against c-spacings of the clay platelet aggregates which widened as a result of polypeptide addition and adsorption before the polymerization, does not permit an obvious explanation of these observations. The best correlation assigns a role to the fractional occupation of the individual intercalation layers of the polypeptides, as the adsorption increases towards a first complete mono-interlayer, then to an incipient and eventually to a complete double layer on to a third interlayer, after which the clay stacking breaks up. Spacings which correspond to an intermediate occupation of any of the three successive interlayers favor amino acids self-addition to polymers. The opposite is true for nearly empty or filled intercalation layers. We hypothesize and describe, how a catalytic activity may derive from c-spacings that offer adsorption sites for the reagent amino acid adenylate within the peripheral recesses of irregularly stacked clay platelets by bringing the anhydride bonds and neutral amino groups into favorable reaction distances. Moderately filled intercalation spaces may also act as sinks for the newly formed oligomers and facilitate the freeing of reaction sites for the occupation by fresh reagent. The c-spacings required for these mechanisms are the result of the intercalation of the preadsorbed polymer, but similar conditions prevail when polymers are adsorbed as they are generated during polymerization.
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