Evidence map›Paper›PMID 32373932›Full record

ArticleClinical infectious diseases : an official publication of the Infectious Diseases Society of America2020

Reduction in Baseline CD4 Count Testing Following Human Immunodeficiency Virus "Treat All" Adoption in Uganda.

Esther Nasuuna, Mark W Tenforde, Alex Muganzi, Joseph N Jarvis, Yukari C Manabe, Joanita Kigozi

Abstract read
In one paragraph

Article in Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Article
  2. Article
  3. Global Trends in CD4 Count Measurement and Distribution at First Antiretroviral Treatment Initiation.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2025
    Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. The Enduring Burden of Advanced Human Immunodeficiency Virus Disease.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2020
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors.

Esther NasuunaInfectious Diseases Institute, College of Health Sciences, Makerere University, Kampala, Uganda.
Mark W TenfordeDivision of Allergy and Infectious Diseases, Department of Medicine, University of Washington School of Medicine, Seattle, Washington, USA.
Alex MuganziInfectious Diseases Institute, College of Health Sciences, Makerere University, Kampala, Uganda.
Joseph N JarvisDepartment of Clinical Research, Faculty of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, London, United Kingdom.
Yukari C ManabeInfectious Diseases Institute, College of Health Sciences, Makerere University, Kampala, Uganda.
Joanita KigoziInfectious Diseases Institute, College of Health Sciences, Makerere University, Kampala, Uganda.

Funding

HOST DEFENSE TRAINING IN ALLERGY AND INFECTIOUS DISEASEST32AI007044 · NIAID · UNIVERSITY OF WASHINGTON · PI DAVID Neal FREDRICKS · 1985 to 2026
$14.6M
NURTURE:Research Training and Mentoring Program for Career Development of Faculty at Makerere University College of Health SciencesD43TW010132 · FIC · MAKERERE UNIVERSITY COLLEGE OF HEALTH SCIENCES · PI SEWANKAMBO, NELSON K · 2015 to 2019
$4.3M
HIV Co-infections in Uganda: TB, Cryptococcus, and Viral Hepatitis.D43TW009771 · FIC · JOHNS HOPKINS UNIVERSITY · PI CASTELNUOVO, BARBARA, KAMBUGU, ANDREW DDUNGU · 2014 to 2023
$3.3M
Cryptococcal antigen screening for the prevention of cryptococcal meningitis in the HIV "treat-and-treat" era: A prospective cohort and semi-quantitative lateral flow assay validation studyF32AI140511 · NIAID · UNIVERSITY OF WASHINGTON · PI TENFORDE, MARK · 2018 to 2018
$65k
Department of Health RP-2017-08-ST2-012FIC NIH HHS D43 TW009771FIC NIH HHS D43 TW010132Medical Research CouncilNIAID NIH HHS F32 AI140511NIAID NIH HHS T32 AI007044Wellcome Trust
6 · The paper itself

Abstract

Baseline CD4 testing rates declined from 73% to 21% between 2013 and 2018 with adoption of "Treat All" in Uganda. Advanced human immunodeficiency virus (HIV) disease (CD4 count < 200 cells/µL) remained common (24% of those tested in 2018, 83% of whom had World Health Organization stage I/II disease). Despite frequent presentation with advanced HIV disease, CD4 testing has declined dramatically.

Indexed as

HIV InfectionsAntiretroviral Therapy, Highly ActiveCD4 Lymphocyte CountHIVHumansUgandaCD4HIVopportunistic infectionstest-and-treattreat all

Identifiers

PMID32373932
PMCPMC7713677

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.