Evidence map›Paper›PMID 32373710›Full record

ReviewInternational journal of cardiology. Heart & vasculature2020

Diagnosing cardiac amyloidosis in every-day practice: A practical guide for the cardiologist.

Maria Papathanasiou, Alexander Carpinteiro, Christoph Rischpler, Tim Hagenacker, Tienush Rassaf, Peter Luedike

Open access · goldAbstract readReview
In one paragraph

Review in International journal of cardiology. Heart & vasculature, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 2 pooled it
2.0field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 2 syntheses or guidelines pooled it, 33 citations in OpenAlex.

  1. Guideline
  2. Pooled it
  3. Mechanisms of damage and therapies for cardiac amyloidosis: a role for inflammation?Clinical research in cardiology : official journal of the German Cardiac Society · 2026
    Review
  4. Review
  5. Article
  6. Review
  7. Review
  8. Review
  9. Article
  10. Article
  11. Article
  12. Article
  13. Clinical Clues and Diagnostic Workup of Cardiac Amyloidosis.Methodist DeBakey cardiovascular journal · 2022
    Review
  14. Article
  15. Review
  16. Article
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Maria PapathanasiouDepartment of Cardiology and Vascular Medicine, West German Heart and Vascular Center, University Hospital Essen, Hufelandstrasse 55, 45147 Essen, Germany.
Alexander CarpinteiroDepartment of Hematology, University Hospital Essen, Hufelandstrasse 55, 45147 Essen, Germany.
Christoph RischplerDepartment of Nuclear Medicine, University Hospital Essen, Hufelandstrasse 55, 45147 Essen, Germany.
Tim HagenackerDepartment of Neurology, University Hospital Essen, Hufelandstrasse 55, 45147 Essen, Germany.
Tienush RassafDepartment of Cardiology and Vascular Medicine, West German Heart and Vascular Center, University Hospital Essen, Hufelandstrasse 55, 45147 Essen, Germany.
Peter LuedikeDepartment of Cardiology and Vascular Medicine, West German Heart and Vascular Center, University Hospital Essen, Hufelandstrasse 55, 45147 Essen, Germany.
Essen University Hospital · DEWest German Heart and Vascular Center Essen · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cardiac amyloidosis (CA) has emerged as a previously underestimated cause of heart failure and mortality. Underdiagnosis resulted mainly from unawareness of the true disease prevalence and the non-specific symptoms of the disease. CA results from extracellular deposition of misfolded protein fibrils, commonly derived from transthyretin (ATTR) or immunoglobulin light chains (AL). A significant proportion of older patients with heart failure and other extracardiac manifestations suffer from ATTR-CA, whereas AL-CA is still considered a rare disease. This article provides an overview of CA with a special focus on current and emerging diagnostic modalities. Furthermore, we provide a diagnostic algorithm for the evaluation of patients with suspected CA in every-day practice.

Indexed as

99mTc-DPD, 99mTc-3,3-diphosphono-1,2-propanodicarboxylic acidAA, amyloid A amyloidosisAApoA-1, apolipoprotein A-1 amyloidosisAL, light chain amyloidosisAmyloidosisATTR, transthyretin amyloidosisATTRv, variant transthyretin amyloidosisATTRwt, wild type transthyretin amyloidosisCA, cardiac amyloidosisCardiomyopathyECV, Extracellular volumeEMB, endomyocardial biopsyHeart failureLGE, late gadolinium enhancementLight chainsLV, left ventricular/ left ventricularMGUS, monoclonal gammopathy of undetermined significanceMRI, magnetic resonance imagingNT-proBNP, N-terminal pro B-type natriuretic peptidePET, positron-emission tomographySPECT, single photon emission computed tomographyTransthyretin

Identifiers

PMID32373710
PMCPMC7191222
OpenAlexW3018593581

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.