Evidence map›Paper›PMID 32373548›Full record

ArticleFrontiers in cellular and infection microbiology2020

Small Animal Model of Post-chemotherapy Tuberculosis Relapse in the Setting of HIV Co-infection.

Matthew B Huante, Tais B Saito, Rebecca J Nusbaum, Kubra F Naqvi, Sadhana Chauhan, Robert L Hunter, Jeffrey K Actor, Jai S Rudra, Mark A Endsley, Joshua G Lisinicchia and 2 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in cellular and infection microbiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
0.3field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 25 citations in OpenAlex.

  1. Applications of humanized mice inMolecular medicine reports · 2026
    Review
  2. Article
  3. Article
  4. Article
  5. Immune Responses toBiomedicines · 2024
    Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Review
  12. The Many Hosts of Mycobacteria 9 (MHM9): A conference report.Tuberculosis (Edinburgh, Scotland) · 2023
    Article
  13. Article
  14. Article
  15. Review
  16. Pathogenesis of Human Immunodeficiency Virus-Journal of clinical medicine · 2020
    Review
  17. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 4 institutions in 1 country.

Matthew B HuanteDepartment of Microbiology and Immunology, University of Texas Medical Branch, Galveston, TX, United States.
Tais B SaitoDepartment of Pathology, University of Texas Medical Branch, Galveston, TX, United States.
Rebecca J NusbaumDepartment of Microbiology, University of Pennsylvania, Philadelphia, PA, United States.
Kubra F NaqviDepartment of Pathology, University of Texas Medical Branch, Galveston, TX, United States.
Sadhana ChauhanDepartment of Microbiology and Immunology, University of Texas Medical Branch, Galveston, TX, United States.
Robert L HunterDepartment of Pathology and Laboratory Medicine, University of Texas Health Sciences Center, Houston, TX, United States.
Jeffrey K ActorDepartment of Pathology and Laboratory Medicine, University of Texas Health Sciences Center, Houston, TX, United States.
Jai S RudraDepartment of Biomedical Engineering, Washington University in St. Louis, St. Louis, MO, United States.
Mark A EndsleyDepartment of Microbiology and Immunology, University of Texas Medical Branch, Galveston, TX, United States.
Joshua G LisinicchiaDepartment of Pathology, University of Texas Medical Branch, Galveston, TX, United States.
Benjamin B GelmanDepartment of Pathology, University of Texas Medical Branch, Galveston, TX, United States.
Janice J EndsleyDepartment of Microbiology and Immunology, University of Texas Medical Branch, Galveston, TX, United States.
The University of Texas Medical Branch at Galveston · USThe University of Texas Health Science Center at Houston · USUniversity of Pennsylvania · USWashington University in St. Louis · US

Funding

Role of IL-17 Cytokine Networks in TB Relapse Due to HIVR01AI147948 · NIAID · UNIVERSITY OF TEXAS MED BR GALVESTON · PI AMUKOYE, EVANS I, ENDSLEY, JANICE J · 2019 to 2023
$3.0M
HIV-induced Defects in Pulmonary Macrophages Exacerbate Mycobacterium Tuberculosis Co-infectionR01HL129881 · NHLBI · UNIVERSITY OF TEXAS MED BR GALVESTON · PI ENDSLEY, JANICE J, GELMAN, BENJAMIN B. · 2016 to 2018
$2.1M
HIV-induced Defects in Pulmonary Macrophages Exacerbate Mycobacterium Tuberculosis Co-infectionR56HL129881 · NHLBI · UNIVERSITY OF TEXAS MED BR GALVESTON · PI ENDSLEY, JANICE J, GELMAN, BENJAMIN B. · 2015 to 2015
$638k
NHLBI NIH HHS R01 HL129881NHLBI NIH HHS R56 HL129881NIAID NIH HHS R01 AI147948
6 · The paper itself

Abstract

Tuberculosis relapse following drug treatment of active disease is an important global public health problem due to the poorer clinical outcomes and increased risk of drug resistance development. Concurrent infection with HIV, including in those receiving anti-retroviral therapy (ART), is an important risk factor for relapse and expansion of drug resistant

Indexed as

CoinfectionHIV InfectionsMycobacterium tuberculosisTuberculosisAnimalsAntitubercular AgentsDisease Models, AnimalMiceRecurrenceAntitubercular AgentsHIVimmune responsepathologyTBTB and HIV co-infectionTB chemotherapyTB relapsetuberculosis

Identifiers

PMID32373548
PMCPMC7176873
OpenAlexW3016570230

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.