Evidence map›Paper›PMID 32373516›Full record

ArticleFrontiers in oncology2020

Case Report of Complete Radiological Response of a Thalamic Glioblastoma After Treatment With Proton Therapy Followed by Temozolomide and Tumor-Treating Fields.

Marco Stein, Hildegard Dohmen, Bernhard Wölk, Fabian Eberle, Malgorzata Kolodziej, Till Acker, Eberhard Uhl, Alexandra Jensen

Open access · goldAbstract readCase Reports
In one paragraph

Article in Frontiers in oncology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.9field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 9 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Marco SteinDepartment of Neurosurgery, Justus-Liebig University, Giessen, Germany.
Hildegard DohmenInstitute of Neuropathology, Justus-Liebig University, Giessen, Germany.
Bernhard WölkDepartment of Neuroradiology, Justus-Liebig University, Giessen, Germany.
Fabian EberleDepartment of Radiotherapy and Radiooncology, UKGM Marburg, Marburg, Germany.
Malgorzata KolodziejDepartment of Neurosurgery, Justus-Liebig University, Giessen, Germany.
Till AckerInstitute of Neuropathology, Justus-Liebig University, Giessen, Germany.
Eberhard UhlDepartment of Neurosurgery, Justus-Liebig University, Giessen, Germany.
Alexandra JensenDepartment of Radiation Oncology, UKGM Giessen, Giessen, Germany.
University of Giessen · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Glioblastoma (GBM) is the most common and aggressive primary brain tumor in adults. We present a case of a 42-year-old male patient presenting with headache and vomiting. Imaging demonstrated obstructive hydrocephalus and a ring-enhancing lesion in the right posterior thalamus. After endoscopic third ventriculostomy and stereotactic biopsy, the histopathologic diagnosis of a malignant glioma was confirmed by DNA methylation array as GBM isocitrate dehydrogenase wild type. The patient was treated with combined treatment of chemoradiation with temozolomide (TMZ) including proton boost, TMZ maintenance, and tumor-treating fields. In this case report, complete radiological response was observed 1 year after the end of radiation therapy.

Indexed as

biopsyglioblastomaproton therapyradiological responseTTFields

Identifiers

PMID32373516
PMCPMC7186451
OpenAlexW3019105595

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.