ReviewAdvanced pharmaceutical bulletin2020
The Role of Natural Antioxidants Against Reactive Oxygen Species Produced by Cadmium Toxicity: A Review.
Review in Advanced pharmaceutical bulletin, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 85 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
85 citing papers in PubMed, 281 citations in OpenAlex.
- Industrial effluent-derivedApplied and environmental microbiology · 2026Article
- Aloesin mitigates cisplatin-induced nephrotoxicity by suppressing NF-κB-mediated oxidative stress and modulating Bax/Bcl-2/caspase pathways.Naunyn-Schmiedeberg's archives of pharmacology · 2026Article
- Heavy Metal Air Pollution: Human Health Effects and Nanomaterial Strategies for Monitoring and Remediation.Biological trace element research · 2026Review
- The ameliorate effect of 18-beta glycyrrhetinic acid against cadmium-induced reproductive damage.Journal of molecular histology · 2026Article
- Subchronic Cadmium-Induced Xenobiotic Toxicity in Male Wistar Rats: Antioxidant and Reproductive Protection by Standardized Silymarin with Molecular Docking Insights.Journal of xenobiotics · 2026Article
- Cerebroprotective potential of ceftriaxone against cadmium chloride-induced cerebral inflammatory changes and oxidative insult.Naunyn-Schmiedeberg's archives of pharmacology · 2026Article
- Combatting Cadmium Toxicity in Animals with Nature-Derived Remedies: Mechanisms and Mitigation.Biological trace element research · 2026Review
- Association between zinc consumption and chronic diarrhea based on NHANES 2005 to 2010 data.Medicine · 2026Article
- Investigation of the preventive action of rebamipide versus cadmium nephrotoxicity effect in rats.Irish journal of medical science · 2026Article
- Physiological Responses, Cadmium Partitioning, and Mineral Nutrient Disruption inPlants (Basel, Switzerland) · 2026Article
- Article
- Association between plasma metal element profiles and cognitive impairment in occupationally aluminum-exposed workers at a large aluminum plant in northern China.The journal of prevention of Alzheimer's disease · 2026Article
- Cadmium-Induced Testicular and Spermatogonial Damage Ameliorated by Bryonia laciniosa Linn. Seeds in Wistar Rats: An Animal Study.Biological trace element research · 2026Article
- Ecotoxicological Impacts of Microplastics and Cadmium Pollution on Wheat Seedlings.Nanomaterials (Basel, Switzerland) · 2026Article
- Soil health to human health: impacts of soil contaminants on cardio-neurological health and clinical outcomes: a narrative review.Frontiers in cardiovascular medicine · 2026Review
- Design, Spectroscopic Elucidation, Bio-Photonic (Optical) Evaluation of Novel Cd-Based Macrocyclic Complexes.Journal of fluorescence · 2026Article
- Article
- Heavy Metal-Contaminated Soils and Gastric Cancer Risk: Molecular Insights and the Relevance of a One Health Perspective.International journal of molecular sciences · 2025Review
- Exercise intensity-mediated regulation of gut epithelial cells and immune function in gut microbiota dysbiosis.Journal of translational medicine · 2025Review
- Selenoprotein M Protects Intestinal Health in Nickel-Exposed Mice: Implications for Animal Welfare Under Heavy Metal Stress.Veterinary sciences · 2025Article
25 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Cadmium (Cd) is a significant ecotoxic heavy metal that adversely affects all biological processes of humans, animals and plants. Exposure to acute and chronic Cd damages many organs in humans and animals (e.g. lung, liver, brain, kidney, and testes). In humans, the Cd concentration at birth is zero, but because the biological half-life is long (about 30 years in humans), the concentration increases with age. The industrial developments of the last century have significantly increased the use of this metal. Especially in developing countries, this consumption is higher. Oxidative stress is the imbalance between antioxidants and oxidants. Cd increases reactive oxygen species (ROS) production and causes oxidative stress. Excess cellular levels of ROS cause damage to proteins, nucleic acids, lipids, membranes and organelles. This damage has been associated with various diseases. These include cancer, hypertension, ischemia/perfusion, cardiovascular diseases, chronic obstructive pulmonary disease, diabetes, insulin resistance, acute respiratory distress syndrome, idiopathic pulmonary fibrosis, asthma, skin diseases, chronic kidney disease, eye diseases, neurodegenerative diseases (amyotrophic lateral sclerosis, Parkinson's disease, Alzheimer's disease, and Huntington disease). Natural antioxidants are popular drugs that are used by the majority of people and have few side effects. Natural antioxidants play an important role in reducing free radicals caused by Cd toxicity. Our goal in this review is to establish the relationship between Cd and oxidative stress and to discuss the role of natural antioxidants in reducing Cd toxicity.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.