Evidence map›Paper›PMID 32373369›Full record

ArticleAdvances in orthopedics2020

Efficacy of the Combined Administration of Systemic and Intra-Articular Tranexamic Acid in Total Hip Arthroplasty Secondary to Femoral Neck Fracture: A Retrospective Study.

Joseph Maalouly, Antonios Tawk, Rami Ayoubi, Georges Katoul Al Rahbani, Aida Metri, Elias Saidy, Gerard El-Hajj, Alexandre Nehme

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Advances in orthopedics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
0.7field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it, 10 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Joseph MaaloulyDepartment of Orthopedic Surgery and Traumatology, Saint George Hospital University Medical Center, Balamand University, P.O. Box 166378, Achrafieh, Beirut 1100 2807, Lebanon.ORCID https://orcid.org/0000-0002-3893-6950
Antonios TawkFaculty of Medicine and Medical Sciences, University of Balamand, Aschrafieh, Beirut, Lebanon.
Rami AyoubiDepartment of Orthopedic Surgery and Traumatology, Saint George Hospital University Medical Center, Balamand University, P.O. Box 166378, Achrafieh, Beirut 1100 2807, Lebanon.ORCID https://orcid.org/0000-0002-3319-6471
Georges Katoul Al RahbaniFaculty of Medicine and Medical Sciences, University of Balamand, Aschrafieh, Beirut, Lebanon.
Aida MetriFaculty of Medicine and Medical Sciences, University of Balamand, Aschrafieh, Beirut, Lebanon.
Elias SaidyDepartment of Orthopedic Surgery and Traumatology, Saint George Hospital University Medical Center, Balamand University, P.O. Box 166378, Achrafieh, Beirut 1100 2807, Lebanon.
Gerard El-HajjDepartment of Medical Imaging and Radiology, Saint George Hospital University Medical Center, Balamand University, P.O. Box 166378, Achrafieh, Beirut 1100 2807, Lebanon.ORCID https://orcid.org/0000-0002-8896-8280
Alexandre NehmeDepartment of Orthopedic Surgery and Traumatology, Saint George Hospital University Medical Center, Balamand University, P.O. Box 166378, Achrafieh, Beirut 1100 2807, Lebanon.ORCID https://orcid.org/0000-0002-8526-0017
University of Balamand · LB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundTotal hip arthroplasty (THA) is associated with substantial blood loss in the postoperative course. Tranexamic acid (TXA) is a potent antifibrinolytic agent, routinely administered by intravenous (IV) and topical (intra-articular, IA) route, which can possibly interrupt the cascade of events due to hemostatic irregularities close to the source of bleeding. However, scientific evidence of combined administration of TXA in THA secondary to a femoral neck fracture is still meagre. The present study aims to compare the patients who were administered combined IV and topical TXA with a control group in terms of blood loss, transfusion rate, and incidence of deep vein thrombosis (DVT) and thromboembolism (TE).

resultsCombined usage of IV and IA TXA showed better results when compared to the control group in terms of blood transfusion rate (31%) and hemoglobin drop (28%). No cases of DVT or TE were noted among the two study groups.

conclusionCombined use of IV and IA TXA provided significantly better results compared to no TXA use with respect to all variables related to postoperative blood loss in THA. Moreover, TXA use is safe in terms of incidence of symptomatic DVT and TE.

Identifiers

PMID32373369
PMCPMC7196961
OpenAlexW3018040167

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.