Evidence map›Paper›PMID 32373218›Full record

ArticleTheranostics2020

Heritable modifiers of the tumor microenvironment influence nanoparticle uptake, distribution and response to photothermal therapy.

Gayatri Sharma, Jaidip M Jagtap, Abdul K Parchur, Venkateswara R Gogineni, Sophia Ran, Carmen Bergom, Sarah B White, Michael J Flister, Amit Joshi

Open access · goldAbstract read
In one paragraph

Article in Theranostics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.3field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 15 citations in OpenAlex.

  1. 2Molecular imaging and biology · 2024
    Article
  2. Review
  3. Article
  4. Imaging-guided nanomedicine development.Current opinion in chemical biology · 2021
    Review
  5. Article
  6. Article
  7. DNA Nanostructures and DNA-Functionalized Nanoparticles for Cancer Theranostics.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2020
    Review
  8. Article
  9. Article
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Gayatri SharmaDepartment of Biomedical Engineering, Medical College of Wisconsin, Milwaukee, WI, USA.
Jaidip M JagtapDepartment of Biomedical Engineering, Medical College of Wisconsin, Milwaukee, WI, USA.
Abdul K ParchurDepartment of Biomedical Engineering, Medical College of Wisconsin, Milwaukee, WI, USA.
Venkateswara R GogineniDepartment of Radiology, Medical College of Wisconsin, Milwaukee, WI, USA.
Sophia RanSimmons Cancer Institute, Southern Illinois University School of Medicine, Springfield, IL, USA.
Carmen BergomDepartment of Radiation Oncology, Medical College of Wisconsin, Milwaukee, WI, USA.
Sarah B WhiteDepartment of Radiology, Medical College of Wisconsin, Milwaukee, WI, USA.
Michael J FlisterDepartment of Physiology, Medical College of Wisconsin, Milwaukee, WI, USA.
Amit JoshiDepartment of Biomedical Engineering, Medical College of Wisconsin, Milwaukee, WI, USA.
Medical College of Wisconsin · USSouthern Illinois University School of Medicine · US

Funding

Leveraging genetic mapping for personalized targeting of breast cancer microenvironmentR01CA193343 · NCI · MEDICAL COLLEGE OF WISCONSIN · PI Amit Joshi · 2015 to 2026
$3.5M
Clinical and Translational Science AwardKL2TR000056 · NCATS · MEDICAL COLLEGE OF WISCONSIN · PI SHAKER, REZA NONE · 2012 to 2015
$609k
NCATS NIH HHS KL2 TR000056NCI NIH HHS R01 CA193343
6 · The paper itself

Abstract

We report the impact of notch-DLL4-based hereditary vascular heterogeneities on the enhanced permeation and retention (EPR) effect and plasmonic photothermal therapy response in tumors.

Indexed as

AnimalsBreast NeoplasmsCell Line, TumorFemaleHumansNanomedicineNanoparticlesPhotothermal TherapyRatsTumor MicroenvironmentBreast CancerNanoparticlesPhotothermalTumor MicroenvironmentTumor Vasculature

Identifiers

PMID32373218
PMCPMC7196309
OpenAlexW3016020264

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.