Evidence map›Paper›PMID 32373173›Full record

ArticleAdvances in hematology2020

Dental and Periodontal Treatment Need after Dental Clearance Is Not Associated with the Outcome of Induction Therapy in Patients with Acute Leukemia: Results of a Retrospective Pilot Study.

Gerhard Schmalz, Lulzim Tulani, Rilana Busjan, Rainer Haak, Tanja Kottmann, Lorenz Trümper, Justin Hasenkamp, Dirk Ziebolz

Open access · goldAbstract read
In one paragraph

Article in Advances in hematology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.6field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. Oral Hygiene Considerations in Adult Patients with Leukemia during a Cycle of Chemotherapy.International journal of environmental research and public health · 2022
    Article
  2. Article
  3. Bundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Gerhard SchmalzDept. of Cariology, Endodontology and Periodontology, University of Leipzig, Leipzig, Germany.
Lulzim TulaniDept. of Cariology, Endodontology and Periodontology, University of Leipzig, Leipzig, Germany.
Rilana BusjanDept. of Cariology, Endodontology and Periodontology, University of Leipzig, Leipzig, Germany.
Rainer HaakDept. of Cariology, Endodontology and Periodontology, University of Leipzig, Leipzig, Germany.
Tanja KottmannClinical Research Organization, Hamm, Germany.
Lorenz TrümperClinic for Hematology and Medical Oncology, University Medical Center Goettingen, Göttingen, Germany.
Justin HasenkampClinic for Hematology and Medical Oncology, University Medical Center Goettingen, Göttingen, Germany.
Dirk ZiebolzDept. of Cariology, Endodontology and Periodontology, University of Leipzig, Leipzig, Germany.ORCID https://orcid.org/0000-0002-9810-2368
Leipzig University · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This retrospective pilot study aimed to detect whether remaining dental/periodontal treatment need and periodontal inflammation after dental clearance would be associated with the initial therapy outcome of adult patients with acute leukemia undergoing induction chemotherapy. Different parameters were assessed from the patients' records: initial blood parameters, blood parameters during initial chemotherapy, leukemia/therapy related complaints, duration of fever, microbiological findings (blood and urine), as well as patients' survival. Dental treatment need was defined as the presence of at least one carious tooth; periodontal treatment need was determined by the presence of probing depth ≥3.5 mm in at least two sextants. To reflect periodontal inflammation, the periodontal inflamed surface area (PISA) was applied. Thirty-nine patients were included. A dental treatment need of 75% and periodontal treatment need of 76% as well as an average PISA of 153.18 ± 158.09 were found. Only two associations were detected: periodontal treatment need was associated with thrombocyte count after 7 days (

Identifiers

PMID32373173
PMCPMC7191429
OpenAlexW3019299956

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.