ReviewFrontiers in plant science2020
Risk Assessment Considerations for Genetically Modified RNAi Plants: EFSA's Activities and Perspective.
Review in Frontiers in plant science, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
25 citing papers in PubMed.
- Noncoding RNAs as tools for advancing translational biology in plants.The Plant cell · 2025Review
- Risk assessment considerations for RNAi-based genetically modified plants.EFSA journal. European Food Safety Authority · 2025Article
- Using transcriptome analysis to evaluate the impact ofFrontiers in plant science · 2025Article
- Classification of and detection techniques for RNAi-induced effects in GM plants.Frontiers in plant science · 2025Review
- Spray-induced gene silencing for crop protection: recent advances and emerging trends.Frontiers in plant science · 2025Review
- RNA Interference Applied to Crustacean Aquaculture.Biomolecules · 2024Review
- Host-Delivered RNA Interference for Durable Pest Resistance in Plants: Advanced Methods, Challenges, and Applications.Molecular biotechnology · 2024Review
- CRISPR/Cas9-induced knockout of an amino acid permease gene (AAP6) reduced Arabidopsis thaliana susceptibility to Meloidogyne incognita.BMC plant biology · 2024Article
- Leveraging RNA interference technology for selective and sustainable crop protection.Frontiers in plant science · 2024Review
- A nematode-inducible promoter can effectively drives RNAi construct to confer Meloidogyne incognita resistance in tomato.Plant cell reports · 2023Article
- Silencing of ATP Synthase β Impairs Egg Development in the LeafhopperInternational journal of molecular sciences · 2022Article
- RNA Interference-Based Genetic Engineering Maize Resistant toFrontiers in plant science · 2022Article
- Off-target effects of RNAi correlate with the mismatch rate between dsRNA and non-target mRNA.RNA biology · 2021Article
- Development and Adoption of Genetically Engineered Plants for Virus Resistance: Advances, Opportunities and Challenges.Plants (Basel, Switzerland) · 2021Review
- Optimizing Efficient RNAi-Mediated Control of Hemipteran Pests (Psyllids, Leafhoppers, Whitefly): Modified Pyrimidines in dsRNA Triggers.Plants (Basel, Switzerland) · 2021Article
- Recent Progress in Enhancing Fungal Disease Resistance in Ornamental Plants.International journal of molecular sciences · 2021Review
- Tuning Beforehand: A Foresight on RNA Interference (RNAi) and In Vitro-Derived dsRNAs to Enhance Crop Resilience to Biotic and Abiotic Stresses.International journal of molecular sciences · 2021Review
- RNAi efficacy is enhanced by chronic dsRNA feeding in pollen beetle.Communications biology · 2021Article
- dsRNA-Mediated Pest Management ofInsects · 2021Article
- Article
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Genetically modified plants (GMPs) intended for market release can be designed to induce "gene silencing" through RNA interference (RNAi). The European Food Safety Authority (EFSA) and other international risk assessment bodies/regulatory agencies have taken several actions to determine whether the existing risk assessment approaches for GMPs are appropriate for the risk assessment of RNAi-based GMPs or require complementary or alternative approaches. To our knowledge, at the international level, no dedicated guidelines have been developed for the risk assessment and regulation of RNAi-based GMPs, confirming that existing science-based risk assessment approaches for GMPs are generally considered suitable for RNAi-based GMPs. However, some specificities have been identified for the risk assessment of RNAi-based GMPs. Here, we report on some of these specificities as identified and addressed by the EFSA GMO Panel for the molecular characterisation, food/feed safety assessment and environmental risk assessment of RNAi-based GMPs, using the DvSnf7 dsRNA-expressing maize MON87411 as a case study.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.