Evidence map›Paper›PMID 32373123›Full record

ArticleFrontiers in immunology2020

Comprehensive Evolutionary Analysis of Lamprey TNFR-Associated Factors (TRAFs) and Receptor-Interacting Protein Kinase (RIPKs) and Insights Into the Functional Characterization of TRAF3/6 and RIPK1.

Jianqiang Hou, Yue Pang, Qingwei Li

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.9field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 19 citations in OpenAlex.

  1. Article
  2. Article
  3. Molecular Characterization of Nine TRAF Genes in Yellow Catfish (International journal of molecular sciences · 2023
    Article
  4. Article
  5. Review
  6. Comparative and evolutionary analysis ofFrontiers in genetics · 2022
    Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Jianqiang HouCollege of Life Sciences, Liaoning Normal University, Dalian, China.
Yue PangCollege of Life Sciences, Liaoning Normal University, Dalian, China.
Qingwei LiCollege of Life Sciences, Liaoning Normal University, Dalian, China.
Liaoning Normal University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

TNFR-associated factors (TRAFs) and receptor-interacting protein kinases (RIPKs) are important immunological linker molecules in mammals and play important roles in the TNFα, TLR and IFN signaling pathways. However, the evolutionary origins of these genes in vertebrates have not previously been described in lampreys. In this study, we searched the genomes of

Indexed as

AnimalsBiological EvolutionFish ProteinsHumansLampreysMultigene FamilyPhylogenyReceptor-Interacting Protein Serine-Threonine KinasesSequence AlignmentStructure-Activity RelationshipTNF Receptor-Associated Factor 3TNF Receptor-Associated Factor 6Fish ProteinsReceptor-Interacting Protein Serine-Threonine KinasesTNF Receptor-Associated Factor 3TNF Receptor-Associated Factor 6evoluationimmune regulationlampreyRIPK familyTRAF family

Identifiers

PMID32373123
PMCPMC7179693
OpenAlexW3016441435

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.