Evidence map›Paper›PMID 32372954›Full record

ArticleFrontiers in pharmacology2020

Pain Following the Use of Anesthesia Formulation Among Individuals Undergoing Cataract Surgery: A Randomized Controlled Trial.

Mario D Toro, Dominika Nowakowska, Agnieszka Brzozowska, Michele Reibaldi, Teresio Avitabile, Claudio Bucolo, Paolo Murabito, Clara Chisari, Katarzyna Nowomiejska, Robert Rejdak

Open access · goldAbstract read
In one paragraph

Article in Frontiers in pharmacology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.6field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. A survey of anaesthetic preferences in cataract surgery.International journal of ophthalmology · 2022
    Article
  3. Article
  4. Ocular Involvement of SARS-CoV-2 in a Polish Cohort of COVID-19-Positive Patients.International journal of environmental research and public health · 2021
    Article
  5. Review
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 2 countries.

Mario D ToroDepartment of General Ophthalmology, Medical University of Lublin, Lublin, Poland.
Dominika NowakowskaDepartment of General Ophthalmology, Medical University of Lublin, Lublin, Poland.
Agnieszka BrzozowskaDepartment of Mathematics and Medical Biostatistics, Medical University of Lublin, Lublin, Poland.
Michele ReibaldiDepartment of Ophthalmology, School of Medicine, University of Catania, Catania, Italy.
Teresio AvitabileDepartment of Ophthalmology, School of Medicine, University of Catania, Catania, Italy.
Claudio BucoloDepartment of Biomedical and Biotechnological Sciences, School of Medicine, University of Catania, Catania, Italy.
Paolo MurabitoDepartment of General Surgery and Surgical Specialties, Division of Anesthesiology, Azienda Ospedaliero-Universitaria Policlinico, Catania, Italy.
Clara ChisariDepartment "GF. Ingrassia", Section of Neurosciences, University of Catania, Catania, Italy.
Katarzyna NowomiejskaDepartment of General Ophthalmology, Medical University of Lublin, Lublin, Poland.
Robert RejdakDepartment of General Ophthalmology, Medical University of Lublin, Lublin, Poland.
Medical University of Lublin · PLUniversity of Catania · ITCardinal Stefan Wyszyński University in Warsaw · PL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo assess the pain intensity of two intracameral anesthetic solutions in patients undergoing cataract surgery and evaluate the factors influencing the patients' postoperative activities.

methodsSixty-two patients undergoing cataract surgery were randomized to receive the study drug - a manufactured solution of 0.02% tropicamide/0.31% phenylephrine/1% lidocaine (Mydrane) or a traditional anesthetic formulation - solution of 1% lidocaine/0.025% adrenaline as an intraocular anesthetic. The pain intensity was assessed by Visual Analog Scale for Pain (VAS Pain) and Brief Pain Inventory-short form (BPI) on the next day after the surgery.

resultsThe mean pain score measured preoperatively with VAS Pain was 0.34 in Mydrane group and 0.09 in the reference group (

conclusionsNew commercially available intraocular anesthetic solution (Mydrane™) seems to be as effective as off-label traditional anesthetic formulation, in reducing the pain experienced during cataract surgery under topical anesthesia.

Indexed as

cataract surgeryintraocular anesthesialidocaineophthalmologic anesthesiapainphenylephrinetropicamide

Identifiers

PMID32372954
PMCPMC7176993
OpenAlexW3017185422

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.