ArticleFrontiers in human neuroscience2020
Path Integration Changes as a Cognitive Marker for Vascular Cognitive Impairment?-A Pilot Study.
Article in Frontiers in human neuroscience, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
20 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Early detection of diseases causing dementia using digital navigation and gait measures: A systematic review of evidence.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2024Pooled it
- Egocentric and Allocentric Spatial Memory in Mild Cognitive Impairment with Real-World and Virtual Navigation Tasks: A Systematic Review.Journal of Alzheimer's disease : JAD · 2021Pooled it
- Gait disorientation as a proxy for impaired spatial navigation: Associations between the Gait Disorientation Test and vestibular-mediated functions.Neuropsychologia · 2025Article
- Review
- Spatial navigation deficits in early Alzheimer's disease: the role of biomarkers and APOE genotype.Journal of neurology · 2025Article
- A cognitive-motor framework for spatial navigation in aging and early-stage Alzheimer's disease.Cortex; a journal devoted to the study of the nervous system and behavior · 2025Review
- Combining patient-lesion and big data approaches to reveal hippocampal contributions to spatial memory and navigation.iScience · 2024Article
- Article
- Bodily and Visual-Cognitive Navigation Aids to Enhance Spatial Recall in Mild Cognitive Impairment.Journal of Alzheimer's disease : JAD · 2024Article
- Embodied Spatial Navigation Training in Mild Cognitive Impairment: A Proof-of-Concept Trial.Journal of Alzheimer's disease : JAD · 2024Article
- Usability of an Embodied CAVE System for Spatial Navigation Training in Mild Cognitive Impairment.Journal of clinical medicine · 2023Article
- Enhancing spatial navigation skills in mild cognitive impairment patients: a usability study of a new version of ANTaging software.Frontiers in human neuroscience · 2023Article
- Spatial orientation - a stable marker for vascular cognitive impairment?Cerebral circulation - cognition and behavior · 2023Article
- Ecological Meanings: A Consensus Paper on Individual Differences and Contextual Influences in Embodied Language.Journal of cognition · 2023Article
- The Split-Half Reliability and Construct Validity of the Virtual Reality-Based Path Integration Task in the Healthy Population.Brain sciences · 2022Article
- Spatial Navigation and Its Association With Biomarkers and Future Dementia in Memory Clinic Patients Without Dementia.Neurology · 2022Article
- Building Embodied Spaces for Spatial Memory Neurorehabilitation with Virtual Reality in Normal and Pathological Aging.Brain sciences · 2021Article
- Cognitive and neuroimaging markers for preclinical vascular cognitive impairment.Cerebral circulation - cognition and behavior · 2021Review
- Spatial Disorientation in Alzheimer's Disease: The Missing Path From Virtual Reality to Real World.Frontiers in aging neuroscience · 2020Article
- Development and validation of the Spatial Navigation and Memory Questionnaire (SPAM).Alzheimer's & dementia (Amsterdam, Netherlands)Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Path integration spatial navigation processes are emerging as promising cognitive markers for prodromal and clinical Alzheimer's disease (AD). However, such path integration changes have been less explored in Vascular Cognitive Impairment (VCI), despite neurovascular change being a major contributing factor to dementia and potentially AD. In particular, the sensitivity and specificity of path integration impairments in VCI compared to AD is unclear. In the current pilot study, we explore path integration performance in early-stage AD and VCI patient groups and hypothesize that: (i) medial parietal mediated egocentric processes will be more affected in VCI; and (ii) medial temporal mediated allocentric processes will be more affected in AD. This cross-sectional study included early-stage VCI patients (
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.