Evidence map›Paper›PMID 32372913›Full record

ArticleFrontiers in neuroscience2020

Concurrent Imaging of Markers of Current Flow and Neurophysiological Changes During tDCS.

Mayank Jog, Kay Jann, Lirong Yan, Yu Huang, Lucas Parra, Katherine Narr, Marom Bikson, Danny J J Wang

Abstract read
In one paragraph

Article in Frontiers in neuroscience, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Mayank JogLaboratory of FMRI Technology, Stevens Neuroimaging and Informatics Institute, University of Southern California, Los Angeles, CA, United States.
Kay JannLaboratory of FMRI Technology, Stevens Neuroimaging and Informatics Institute, University of Southern California, Los Angeles, CA, United States.
Lirong YanLaboratory of FMRI Technology, Stevens Neuroimaging and Informatics Institute, University of Southern California, Los Angeles, CA, United States.
Yu HuangDepartment of Biomedical Engineering, the City College of The City University of New York, New York, NY, United States.
Lucas ParraDepartment of Biomedical Engineering, the City College of The City University of New York, New York, NY, United States.
Katherine NarrDepartment of Neurology, University of California, Los Angeles, Los Angeles, CA, United States.
Marom BiksonDepartment of Biomedical Engineering, the City College of The City University of New York, New York, NY, United States.
Danny J J WangLaboratory of FMRI Technology, Stevens Neuroimaging and Informatics Institute, University of Southern California, Los Angeles, CA, United States.

Funding

Imaging-guided tDCS therapy in major depressionR33MH110526 · NIMH · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI NARR, KATHERINE L · 2020 to 2022
$3.2M
Imaging-guided tDCS therapy in major depressionR61MH110526 · NIMH · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI NARR, KATHERINE L, WANG, DANNY JJ · 2017 to 2018
$2.2M
A tool-box to control and enhance tDCS spatial precisionR01MH111896 · NIMH · CITY COLLEGE OF NEW YORK · PI BIKSON, MAROM · 2016 to 2019
$2.2M
NIMH NIH HHS R01 MH111896NIMH NIH HHS R33 MH110526NIMH NIH HHS R61 MH110526
6 · The paper itself

Abstract

Despite being a popular neuromodulation technique, clinical translation of transcranial direct current stimulation (tDCS) is hampered by variable responses observed within treatment cohorts. Addressing this challenge has been difficult due to the lack of an effective means of mapping the neuromodulatory electromagnetic fields together with the brain's response. In this study, we present a novel imaging technique that provides the capability of concurrently mapping markers of tDCS currents, as well as the brain's response to tDCS. A dual-echo echo-planar imaging (DE-EPI) sequence is used, wherein the phase of the acquired MRI-signal encodes the tDCS current induced magnetic field, while the magnitude encodes the blood oxygenation level dependent (BOLD) contrast. The proposed technique was first validated in a custom designed phantom. Subsequent test-retest experiments in human participants showed that tDCS-induced magnetic fields can be detected reliably

Indexed as

BOLD fMRIcurrent mappingdual-echo echo planar imaging (DE-EPI)resting-statetDCS

Identifiers

PMID32372913
PMCPMC7186453

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.