Evidence map›Paper›PMID 32372872›Full record

ArticleJournal of ginseng research2020

Korean Red Ginseng extract ameliorates melanogenesis in humans and induces antiphotoaging effects in ultraviolet B-irradiated hairless mice.

Evelyn Saba, Seung-Hyung Kim, Yuan Yee Lee, Chae-Kyu Park, Jae-Wook Oh, Tae-Hwan Kim, Hyun-Kyoung Kim, Seong-Soo Roh, Man Hee Rhee

Erratum issuedOpen access · goldAbstract read
In one paragraph

Article in Journal of ginseng research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.5field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 25 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Review
  5. Article
  6. Review
  7. Article
  8. Antimelanogenesis Effects of Theasinensin A.International journal of molecular sciences · 2021
    Article
  9. Anti-Pigmentary Natural Compounds and Their Mode of Action.International journal of molecular sciences · 2021
    Review
  10. The regulatory role of Korean ginseng in skin cells.Journal of ginseng research · 2021
    Review
  11. Inhibitory Effect ofMolecules (Basel, Switzerland) · 2021
    Article
  12. Evidence-based complementary and alternative medicine : eCAM · 2021
    Article
  13. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors at 6 institutions in 1 country.

Evelyn SabaLaboratory of Physiology and Cell Signalling, Kyungpook National University, Daegu, Republic of Korea.
Seung-Hyung KimInstitute of Traditional Medicine and Bioscience, Daejeon University, Daejeon, Republic of Korea.
Yuan Yee LeeLaboratory of Physiology and Cell Signalling, Kyungpook National University, Daegu, Republic of Korea.
Chae-Kyu ParkR&D Headquarters, Korean Ginseng cooperation, Daejeon, Republic of Korea.
Jae-Wook OhDepartment of Stem Cell and Regenerative Biotechnology, Konkuk University, Seoul, Republic of Korea.
Tae-Hwan KimLaboratory of Physiology and Cell Signalling, Kyungpook National University, Daegu, Republic of Korea.
Hyun-Kyoung KimDepartment of Food Science and Engineering, Seowon University, Chungbuk, Republic of Korea.
Seong-Soo RohCollege of Korean Medicine, Daegu Haany University, Daegu, Republic of Korea.
Man Hee RheeLaboratory of Physiology and Cell Signalling, Kyungpook National University, Daegu, Republic of Korea.
Kyungpook National University · KRDaegu Haany University · KRDaejeon University · KRKonkuk University · KRKorean Society of Ginseng · KRSeowon University · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

background

methodsTherefore, in our study, we used the murine melanoma cell line B16/F10 to study the inhibition of melanogenesis by Korean Red Ginseng (KRG) extract

resultsOur results demonstrated that KRG induced potent suppression of tyrosinase activity and melanin production in B16/F10 cells; moreover, it reduced the transcription and translation of components involved in the melanin production pathway. In the

conclusionTherefore, we conclude that KRG is an excellent skin whitening and antiaging product.

Indexed as

AntiagingHuman trialsKorean Red Ginseng extractMelanogenesisWrinkles

Identifiers

PMID32372872
PMCPMC7195593
OpenAlexW2945004000

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.