Evidence map›Paper›PMID 32372769›Full record

ArticleEuropean polymer journal2020

Electrosprayed poly(lactic-co-glycolic acid) particles as a promising drug delivery system for the novel JNK inhibitor IQ-1.

Elina Kibler, Anastasia Lavrinenko, Ilya Kolesnik, Ksenia Stankevich, Evgeny Bolbasov, Valeriya Kudryavtseva, Andrey Leonov, Igor Schepetkin, Andrei Khlebnikov, Mark T Quinn and 1 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in European polymer journal, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Chemistry and Biological Activity of 11Molecules (Basel, Switzerland) · 2026
    Review
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Elina KiblerNational Research Tomsk Polytechnic University, Tomsk 634050, Russia.
Anastasia LavrinenkoNational Research Tomsk Polytechnic University, Tomsk 634050, Russia.
Ilya KolesnikNational Research Tomsk Polytechnic University, Tomsk 634050, Russia.
Ksenia StankevichNational Research Tomsk Polytechnic University, Tomsk 634050, Russia.
Evgeny BolbasovNational Research Tomsk Polytechnic University, Tomsk 634050, Russia.
Valeriya KudryavtsevaNational Research Tomsk Polytechnic University, Tomsk 634050, Russia.
Andrey LeonovNational Research Tomsk Polytechnic University, Tomsk 634050, Russia.
Igor SchepetkinDepartment of Microbiology and Immunology, Montana State University, Bozeman, MT 59717, USA.
Andrei KhlebnikovNational Research Tomsk Polytechnic University, Tomsk 634050, Russia.
Mark T QuinnDepartment of Microbiology and Immunology, Montana State University, Bozeman, MT 59717, USA.
Sergei TverdokhlebovNational Research Tomsk Polytechnic University, Tomsk 634050, Russia.

Funding

Research Core (Developmental Research Project Program)P20GM103474 · NIGMS · MONTANA STATE UNIVERSITY - BOZEMAN · PI Jeffrey Good · 2012 to 2026
$60.0M
Tracking and Evaluation CoreU54GM115371 · NIGMS · MONTANA STATE UNIVERSITY - BOZEMAN · PI KREBS, JOCELYN E · 2016 to 2020
$20.9M
Pilot Grants ProgramP30GM110732 · NIGMS · MONTANA STATE UNIVERSITY - BOZEMAN · PI JUTILA, MARK A · 2014 to 2018
$5.4M
Center for Zoonotic and Emerging Infectious DiseasesP20GM103500 · NIGMS · MONTANA STATE UNIVERSITY - BOZEMAN · PI QUINN, MARK T · 2012 to 2013
$4.2M
NIGMS NIH HHS P20 GM103474NIGMS NIH HHS P20 GM103500NIGMS NIH HHS P30 GM110732NIGMS NIH HHS U54 GM115371
6 · The paper itself

Abstract

Mitogen-activated protein kinases (MAPKs), including c-Jun N-terminal kinase (JNK), play important role in the regulation of pro-inflammatory cytokine secretion and signaling cascades. Therefore, JNKs are key targets for the treatment of cytokine/JNK-driven diseases. Herein, we developed electrospray poly(lactic-co-glycolic acid) (PLGA) microparticles doped with novel JNK inhibitor 11

Indexed as

c-Jun N-terminal kinase inhibitorDrug deliveryElectrosprayPoly(lactic-co-glycolic acid)

Identifiers

PMID32372769
PMCPMC7199471

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.