Observational studyPsychological medicine2021
How do ethnicity and deprivation impact on life expectancy at birth in people with serious mental illness? Observational study in the UK.
Observational study in Psychological medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.
What it found
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
20 citing papers in PubMed, 1 synthesis or guideline pooled it, 26 citations in OpenAlex.
- The Role of Socioeconomic Position in the Association Between Mental Disorders and Mortality: A Systematic Review and Meta-Analysis.JAMA psychiatry · 2024Pooled it
- Using theory of change to better address social and economic needs in mental health services.International journal of mental health systems · 2026Article
- Combinations of mental disorders and their association with mortality in the UK Biobank.BMC psychiatry · 2026Article
- A retrospective and comprehensive analysis of excess life-years lost, mortality risk, and cause of death among severe mental illness in China.BMC medicine · 2025Observational
- Health, Disability, and Economic Inactivity Following a Diagnosis of a Severe Mental Illness: Cohort Study of Electronic Health Records Linked at the Individual-Level, to Census from England.Schizophrenia bulletin · 2025Article
- Time trends in life expectancy of people with severe mental illness in Scotland, 2000-2019: population-based study.BJPsych open · 2025Article
- An examination of inpatient ward and secondary community care stay costs for individuals with complex mental health needs in the UK.PLOS mental health · 2025Article
- Article
- Cardiovascular risk management among individuals with type 2 diabetes and severe mental illness: a cohort study.Diabetologia · 2024Article
- Severe mental illness, race/ethnicity, multimorbidity and mortality following COVID-19 infection: nationally representative cohort study.The British journal of psychiatry : the journal of mental science · 2023Article
- Life expectancy and years of potential life lost in people with mental disorders: a systematic review and meta-analysis.EClinicalMedicine · 2023Article
- Monitoring the Effectiveness of Treatment in Women with Schizophrenia: New Specialized Cooperative Approaches.Brain sciences · 2023Review
- Ethnic disparities in mortality and group-specific risk factors in the UK Biobank.PLOS global public health · 2023Article
- Neoagaro-Oligosaccharides Ameliorate Chronic Restraint Stress-Induced Depression by Increasing 5-HT and BDNF in the Brain and Remodeling the Gut Microbiota of Mice.Marine drugs · 2022Article
- Ethnic inequities in multimorbidity among people with psychosis: a retrospective cohort study.Epidemiology and psychiatric sciences · 2022Article
- Article
- Effects of pharmacological treatment on metabolomic alterations in animal models of depression.Translational psychiatry · 2022Article
- All-cause and cause-specific mortality in people with mental disorders and intellectual disabilities, before and during the COVID-19 pandemic: cohort study.The Lancet regional health. Europe · 2021Article
- Understanding the excess psychosis risk in ethnic minorities: the impact of structure and identity.Social psychiatry and psychiatric epidemiology · 2021Review
- Inequalities in glycemic management in people living with type 2 diabetes mellitus and severe mental illnesses: cohort study from the UK over 10 years.BMJ open diabetes research & care · 2021Article
Corrections and comments
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Authors and funding
8 authors at 2 institutions in 2 countries.
Funding
Abstract
backgroundAcross international contexts, people with serious mental illnesses (SMI) experience marked reductions in life expectancy at birth. The intersection of ethnicity and social deprivation on life expectancy in SMI is unclear. The aim of this study was to assess the impact of ethnicity and area-level deprivation on life expectancy at birth in SMI, defined as schizophrenia-spectrum disorders, bipolar disorders and depression, using data from London, UK.
methodsAbridged life tables to calculate life expectancy at birth, in a cohort with clinician-ascribed ICD-10 schizophrenia-spectrum disorders, bipolar disorders or depression, managed in secondary mental healthcare. Life expectancy in the study population with SMI was compared with life expectancy in the general population and with those residing in the most deprived areas in England.
resultsIrrespective of ethnicity, people with SMI experienced marked reductions in life expectancy at birth compared with the general population; from 14.5 years loss in men with schizophrenia-spectrum and bipolar disorders, to 13.2 years in women. Similar reductions were noted for people with depression. Across all diagnoses, life expectancy at birth in people with SMI was lower than the general population residing in the most deprived areas in England.
conclusionsIrrespective of ethnicity, reductions in life expectancy at birth among people with SMI are worse than the general population residing in the most deprived areas in England. This trend in people with SMI is similar to groups who experience extreme social exclusion and marginalisation. Evidence-based interventions to tackle this mortality gap need to take this into account.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.