Evidence map›Paper›PMID 32372728›Full record

ArticleDevelopment and psychopathology2021

Childhood adversity is linked to adult health among African Americans via adolescent weight gain and effects are genetically moderated.

Steven R H Beach, Mei Ling Ong, Man-Kit Lei, Eric Klopack, Sierra E Carter, Ronald L Simons, Frederick X Gibbons, Justin A Lavner, Robert A Philibert, Kaixiong Ye

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Development and psychopathology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
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  5. Childhood adversity and adult health: A dyadic analysis of Black American couples.Health psychology : official journal of the Division of Health Psychology, American Psychological Association · 2022
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Steven R H BeachDepartment of Psychology, University of Georgia, Athens, GA, USA.ORCID 0000-0001-8053-7761
Mei Ling OngCenter for Family Research, University of Georgia, Athens, GA, USA.
Man-Kit LeiDepartment of Sociology, University of Georgia, Athens, GA, USA.
Eric KlopackDepartment of Sociology, University of Georgia, Athens, GA, USA.
Sierra E CarterDepartment of Psychology, Georgia State University, Atlanta, GA, USA.
Ronald L SimonsDepartment of Sociology, University of Georgia, Athens, GA, USA.
Frederick X GibbonsDepartment of Psychological Sciences, University of Connecticut, Storrs, CT, USA.
Justin A LavnerDepartment of Psychology, University of Georgia, Athens, GA, USA.
Robert A PhilibertDepartment of Psychiatry, University of Iowa, Iowa City, IA, USA.
Kaixiong YeDepartment of Genetics and Institute of Bioinformatics, University of Georgia, Athens, GA, USA.

Funding

Vulnerability to Drug Use & HIV: Advancing Prevention for Rural African AmericansP30DA027827 · NIDA · UNIVERSITY OF GEORGIA · PI BRODY, GENE H. · 2009 to 2018
$10.2M
Contextual and Health Behavior Effects on Epigenetic Aging Among African AmericansR01CA220254 · NCI · UNIVERSITY OF CONNECTICUT STORRS · PI BEACH, STEVEN R, GIBBONS, FREDERICK X · 2018 to 2022
$3.5M
Psychosocial Context and the Biological Clock: Changes in Weathering during Middle-AgeR01AG055393 · NIA · UNIVERSITY OF GEORGIA · PI SIMONS, RONALD L · 2017 to 2021
$3.4M
Biomarkers of Health Risk Among African American CouplesR01HD080749 · NICHD · UNIVERSITY OF GEORGIA · PI BEACH, STEVEN R, SIMONS, RONALD L · 2015 to 2019
$2.9M
Social Determinants of Inflammation and Metabolic Syndrom among African AmericansR01HL118045 · NHLBI · UNIVERSITY OF GEORGIA · PI SIMONS, RONALD L · 2014 to 2017
$2.3M
NCI NIH HHS R01 CA220254NHLBI NIH HHS R01 HL118045NIA NIH HHS R01 AG055393NICHD NIH HHS R01 HD080749NIDA NIH HHS P30 DA027827
6 · The paper itself

Abstract

Identifying the mechanisms linking early experiences, genetic risk factors, and their interaction with later health consequences is central to the development of preventive interventions and identifying potential boundary conditions for their efficacy. In the current investigation of 412 African American adolescents followed across a 20-year period, we examined change in body mass index (BMI) across adolescence as one possible mechanism linking childhood adversity and adult health. We found associations of childhood adversity with objective indicators of young adult health, including a cardiometabolic risk index, a methylomic aging index, and a count of chronic health conditions. Childhood adversities were associated with objective indicators indirectly through their association with gains in BMI across adolescence and early adulthood. We also found evidence of an association of genetic risk with weight gain across adolescence and young adult health, as well as genetic moderation of childhood adversity's effect on gains in BMI, resulting in moderated mediation. These patterns indicated that genetic risk moderated the indirect pathways from childhood adversity to young adult health outcomes and childhood adversity moderated the indirect pathways from genetic risk to young adult health outcomes through effects on weight gain during adolescence and early adulthood.

Indexed as

Adverse Childhood ExperiencesBlack or African AmericanAdolescentAdultBody Mass IndexHumansRisk FactorsWeight GainYoung AdultAfrican Americanchildhood adversitygenetic riskhealth disparitiesobesity

Identifiers

PMID32372728
PMCPMC7644595

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.